TNFAIP3 Interacting Protein 3 (TNIP3) Antikörper

Antigen: TNFAIP3 Interacting Protein 3 (TNIP3)

Synonyme: LIND, ABIN-3, FLJ21162, MGC129495, 9030611K07Rik

Klonalität: Monoklonal (Tgr21A5)

Wirt: Hamster

Reaktivität: Maus

Applikation: Western Blot (WB)

Produktnummer: ABIN313767

Produktbeschreibung

Weitere Bezeichnung: ABIN-3

Immunogen: GST fusion protein corresponding to residues 141-208 of mouse ABIN-3

Format: Purified

Isotyp: IgG  (Passende Sekundärantikörper)

Klon: Tgr21A5

Beschreibung: ABIN-3, also known as LIND, was originally identified as a gene induced in monocytes upon infection by Listeriamonocytogenes. ABIN-3 is induced upon stimulation by IL-10. Expression of human ABIN-3 in cells inhibitedNF-kappa-B activation and proinflammatory gene expression in response to TNF, IL-1, and TLR ligands. In mice,ABIN-3 lacks the AHD2 domain, which explains its inability to inhibit NF-kappa-B in mice.

Anwendungen

Applikationshinweise: Each lot of this antibody is quality control tested by Western blotting. Westernblotting, suggested working dilution(s): Use 5 ug antibody per 5 ml antibodydilution buffer for each mini-gel. It is recommended that the reagent betitrated for optimal performance for each application

Reinigung: The antibody was purified by protein G affinity chromatography

Buffer: This antibody is provided in phosphate-buffered solution, pH 7.2, containing0.09% sodium azide. Final antibody concentration is 0.5 mg/ml.

Lagerung: Upon receipt, store at 4 degrees C.

Beschränkungen: Nur für Forschungszwecke einsetzbar