CD300e Molecule (CD300E) Antikörper

Antigen: CD300e Molecule (CD300E)

Klonalität: Polyklonal

Wirt: Bitte anfragen

Reaktivität: Human

Applikation: Durchflusszytometrie (FACS), Aktivierung (Act), Immunpräzipitation (IP), Immunhistochemie (Gefrierschnitte) (IHC (fro))

Produktnummer: ABIN313722

Produktbeschreibung

Weitere Bezeichnung: IREM-2 (CD300e, CMRF35-A5)

Immunogen: IREM-IgG fusion protein

Format: Purified

Isotyp: IgG1, kappa chain

Klon: UP-H2

Beschreibung: IREM-2 (immune receptor expressed by myeloid cells 2), also known as CMRF35-A5, LMIR6, CD300Le or CD300e,is a 34 kDa type I single transmembrane glycoprotein. It is a member of the CD300 family and of the Ig-superfamily.IREM-2 is expressed on monocyte and myeloid dendritic cells, but not on granulocytes and lymphoid dendritic cells.IREM-2 is an activating receptor through interaction with DAP12.

Anwendungen

Applikationshinweise: Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For immunofluorescent staining, the suggested use of this reagent is approx. 1.0 ug per 106 cells in 100 ul volume. It isrecommended that the reagent be titrated for optimal performance for each application. Additional reported applications include: immunoprecipitation and stimulation of TNF-a production by monocytes

Reinigung: The antibody was purified by affinity chromatography.

Buffer: Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide.

Lagerung: The antibody solution should be stored undiluted at 4 degrees C.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Publikationen

Publikationen: Aguilar, Alvarez-Errico, Garcuia-Montero et al.: "Molecular characterization of a novel immune receptor restricted to the monocytic lineage." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 173, Issue 11, pp. 6703-11, 2004 (PubMed).