» Antikörper » anti-Chemokine (C-C Motif) Receptor 7 (CCR7) Antikörper (PerCP/Cy5.5)

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	+49 (0)241 95 163 153
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Chemokine (C-C Motif) Receptor 7 (CCR7) Antikörper (PerCP/Cy5.5)

Antigen	Chemokine (C-C Motif) Receptor 7 (CCR7)
Synonyme	BLR2, EBI1, CD197, CDw197, CMKBR7, Ebi1h, Cdw197, Cmkbr7, MGC108519, CCR7, MGC165629, zgc:165629
Klonalität	Monoklonal (TG8-CCR7)
Wirt	Alternativen Maus Ratte (27), Kaninchen (19), Maus (5), Ziege (2)
Reaktivität	Alternativen Human Maus (35), Human (26), Ratte (Rattus) (6)
Konjugat	Alternativen PerCP,Cy5.5 Biotin (5), PE (5), APC (3), PE,Cy7 (3), Alexa Fluor 700 (2), PerCP,Cy5.5 (2), Alexa Fluor 488 (1), Alexa Fluor 647 (1)
Applikation	Alternativen Durchflusszytometrie (FACS) Durchflusszytometrie (FACS) (33), Immunhistochemie (Paraffinschnitte) (IHC (p)) (16), Western Blot (WB) (10), Immunfluoreszenz (IF) (5), Immunhistochemie (Gefrierschnitte) (IHC (fro)) (5), Enzyme Immunoassay (EIA) (4), Immunpräzipitation (IP) (4), Funktionale Studien (Func) (1)

Produktnummer	ABIN313323
Menge	25 tests
Preis	195,71 € Zzgl. Versandkosten €20,00 und MWSt
Lieferung nach
Verfügbarkeit	Lieferung in 5 bis 7 Werktagen

Produktbeschreibung
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Weitere Bezeichnung	CD197 (CCR7)
Isotyp	IgG2a, kappa chain
Klon	TG8-CCR7
Beschreibung	CCR7 is a chemokine receptor that binds CCL19 and CCL21 (1). CCR7 and its ligands link innate and adaptiveimmunity through their effects on interactions between T cells and dendritic cells. Naive T cells enter the lymph nodethrough high endothelial venules, which express CCL21. Dendritic cells and macrophages enter the lymph nodethrough afferent lymphatics. The encounter of T cells and dendritic cells in the T cell zone is CCR7-dependent (2). Inaddition, during immunological surveillance, B lymphocytes re-circulate between B-cell-rich compartments (follicles orB zones) in secondary lymphoid organs, surveying for antigen. After antigen binding, B cells move to the boundary ofB and T zones to interact with T-helper cells, this B cell migration is directed by CCR7 and its ligands. CCR7-positivecancer cell expression has been associated to lymph node metastasis.

Anwendungen
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Applikationshinweise	Each lot of this antibody is quality control tested by immunofluorescentstaining with flow cytometric analysis. For immunofluorescent staining, thesuggested use of this reagent is 5 ul per million cells or 5 ul per 100 ul ofwhole blood. It is recommended that the reagent be titrated for optimalperformance for each application. * PerCP/Cy5.5 has a maximum absorption of 482 nm and 564 nm and amaximum emission of 690 nm.
Reinigung	The antibody was purified by affinity chromatography, and conjugated withPerCP/Cy5.5 under optimal conditions. The solution is free of unconjugatedPerCP/Cy5.5 and unconjugated antibody.
Buffer	Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide and0.2% (w/v) BSA (origin USA).
Lagerung	The antibody solution should be stored undiluted at 4 degrees C and protected from prolonged exposure to light. Do not freeze.
Beschränkungen	Nur für Forschungszwecke einsetzbar

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anti-Chemokine (C-C Motif) Receptor 7 (CCR7) antibody (PerCP/Cy5.5)

Alternativen
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Alternativen zu Antigen "Chemokine (C-C Motif) Receptor 7 (CCR7)", Typ "Antikörper" finden

Wirte	Ratte (27), Kaninchen (19), Maus (5), Ziege (2)
Reaktivitäten	Maus (35), Human (26), Ratte (Rattus) (6)
Applikationen	Durchflusszytometrie (FACS) (33), Immunhistochemie (Paraffinschnitte) (IHC (p)) (16), Western Blot (WB) (10), Immunfluoreszenz (IF) (5), Immunhistochemie (Gefrierschnitte) (IHC (fro)) (5), Enzyme Immunoassay (EIA) (4), Immunpräzipitation (IP) (4), Funktionale Studien (Func) (1)
Konjugate	Biotin (5), PE (5), APC (3), PE,Cy7 (3), Alexa Fluor 700 (2), PerCP,Cy5.5 (2), Alexa Fluor 488 (1), Alexa Fluor 647 (1)
Epitope	C-Term (1), N-Term (1)