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Integrin alpha M (ITGAM) Antikörper (PerCP)

Antigen

Integrin alpha M (ITGAM)

Synonyme CR3A, MO1A, CD11B, MAC-1, MAC1A, SLEB6, MGC117044, CR3, MAC1, Cd11b, Ly-40, Mac-1, Mac-1a, CD11b/CD18, F730045J24Rik
Klonalität Monoklonal (M1-70)
Wirt
Alternativen

Ratte

Reaktivität
Alternativen

Maus, Human

Konjugat
Alternativen PerCP
Applikation
Alternativen Durchflusszytometrie (FACS)
Produktnummer ABIN313233
Menge 25 ug  (Varianten)
Preis 111,43 €   Zzgl. Versandkosten €20,00 und MWSt
Lieferung nach
Verfügbarkeit Lieferbar innerhalb von 5 bis 10 Werktagen

Produktbeschreibung

Weitere Bezeichnung CD11b
Immunogen C57BL/10 splenocytesReactivity: MouseCross-
Isotyp IgG2b, kappa
Klon M1-70
Beschreibung CD11b is a 170 kD glycoprotein, also known as alphaM integrin, Mac-1 alpha subunit, Mol, CR3, or Ly-40. CD11b is amember of the integrin family, primarily expressed on granulocytes, monocytes/macrophages, NK cells, and some Tand B cells. CD11b non-covalently associates with CD18 (beta2 integrin) to form Mac-1. Mac-1 plays an important rolein cell-cell interaction by binding its ligands ICAM-1 (CD54), ICAM-2 (CD102), ICAM-4 (CD242), iC3b, and fibrinogen. The M1/70 antibody can block CD11b-mediated cellular adhesion. This antibody is also cross-reactive with humanCD11b.

Anwendungen

Applikationshinweise Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For immunofluorescent staining, the suggested use of this reagent is approx. 0.25 ug per 106 cells in 100 ul volume. It isrecommended that the reagent be titrated for optimal performance for each application. * PerCP has a maximum absorption of 482 nm and 564 nm and a maximum emission of 675 nm. Additional reported applications of this antibody (for the relevant formats) include: immunoprecipitation1, in vitroblocking of cell-cell adhesion2, and immunohistochemistry3-5 of acetone-fixed frozen
Reinigung The antibody was purified by affinity chromatography, and conjugated withPerCP under optimal conditions. The solution is free of unconjugated PerCPand unconjugated antibody.
Buffer Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide.
Lagerung The antibody solution should be stored undiluted at 4 degrees C and protected from prolonged exposure to light. Do not freeze.
Beschränkungen Nur für Forschungszwecke einsetzbar

Alternativen

Alternativen zu Antigen "Integrin alpha M (ITGAM)", Typ "Antikörper" finden
Wirte Ratte (183), Maus (171), Kaninchen (31), Ziege (7)
Reaktivitäten Human (238), Maus (204), Ratte (Rattus) (41), Kaninchen (25), Affe (21), Schaf (20), Schwein (19), Pavian (17), Cynomolgus (17), Rhesusaffen (17), Rind (Kuh) (13), Hund (6), Ziege (4), Primaten (3), Pferd (2), Katze (1), Marder (1)
Applikationen Durchflusszytometrie (FACS) (328), Immunhistochemie (Gefrierschnitte) (IHC (fro)) (101), Immunpräzipitation (IP) (87), Western Blot (WB) (30), Immunfluoreszenz (IF) (21), Funktionale Studien (Func) (20), Immunhistochemie (IHC) (20), Immunhistochemie (Paraffinschnitte) (IHC (p)) (18), Blockierende Antikörper (Inhibition) (17), Enzyme Immunoassay (EIA) (7), ELISA (3), Immunzytochemie (ICC) (3), Radioimmunoassay (RIA) (3), Dot Blot (Dot) (2)
Konjugate FITC (56), PE (44), Biotin (41), APC (14), PE/Cy5 (8), PE/Cy7 (8), Cy5 (7), Alexa Fluor 488 (6), Alexa Fluor 647 (6), APC/Cy7 (4), Alexa Fluor 700 (4), Pacific Blue (4), PerCP/Cy5.5 (4), RPE (4), SPRD (4), APC,Cy7 (1), HRP (1), PE,Cy5 (1), PE,DY647 (1), PE-Dyomics 647 (1), PerCP (1), RPE,Cy5 (1)
Epitope C-Term (1)