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Complement Decay-Accelerating Factor (CD55) Antikörper (PE/Cy7)

Antigen

Complement Decay-Accelerating Factor (CD55)

Synonyme CR, TC, DAF, CROM
Klonalität Monoklonal (JS11)
Wirt
Reaktivität
Alternativen

Human

Konjugat
Alternativen PE,Cy7
Applikation
Alternativen Durchflusszytometrie (FACS)
Produktnummer ABIN313179
Menge 100 tests
Preis 337,14 €   Zzgl. Versandkosten €20,00 und MWSt
Lieferung nach
Verfügbarkeit Lieferung in 5 bis 7 Werktagen

Produktbeschreibung

Weitere Bezeichnung CD55
Isotyp IgG1, kappa chain
Klon JS11
Beschreibung CD55 is a 60-70 kD glycosylphosphatidylinositol (GPI)-anchored single chain glycoprotein also known asdecay-accelerating factor (DAF). It is expressed on hematopoietic cells including erythrocytes and manynon-hematopoietic cells. CD55 accelerates the dissociation of the components of the C3-convertases (namely C2afrom C4b in the C4bC2a complex, a C3-convertase of the classical pathway, and factor Bb from the C3bBb complex,a C3-convertase of the alternative pathway) to protect cells from inappropriate damage caused by autologouscomplement. CD55 has been reported to reduce the efficiency of NK cell lysis and induce signal transduction in Tcells. CD55 has also been shown to interact with CD97 and bind to Coxsackie and Echovirus.

Anwendungen

Applikationshinweise Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For immunofluorescent staining, the suggested use of this reagent is 20 ul per million cells or 20 ul per 100 ul of wholeblood. It is recommended that the reagent be titrated for optimal performance for each application.
Reinigung The antibody was purified by affinity chromatography, and conjugated withPE/Cy7 under optimal conditions. The solution is free of unconjugatedPE/Cy7 and unconjugated antibody.
Buffer Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide and0.2% (w/v) BSA (origin USA).
Lagerung The antibody solution should be stored undiluted at 4 degrees C and protected from prolonged exposure to light. Do not freeze.
Beschränkungen Nur für Forschungszwecke einsetzbar

Alternativen

Alternativen zu Antigen "Complement Decay-Accelerating Factor (CD55)", Typ "Antikörper" finden
Wirte Maus (79), Hamster (4), Kaninchen (4), Huhn (1), Ratte (1)
Reaktivitäten Human (77), Primaten (6), Maus (5), Meerschweinchen (3)
Applikationen Durchflusszytometrie (FACS) (81), Western Blot (WB) (16), Immunhistochemie (Gefrierschnitte) (IHC (fro)) (15), Immunpräzipitation (IP) (13), Immunhistochemie (IHC) (8), Immunhistochemie (Paraffinschnitte) (IHC (p)) (5), ELISA (4)
Konjugate FITC (16), Biotin (12), PE (12), RPE (4), APC (2), Alexa Fluor 488 (1), Alexa Fluor 700 (1), BIMA (1), Cy5,PE (1), PE,Cy5 (1), Pacific Blue (1), SPRD (1)