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Lectin, Galactoside-Binding, Soluble, 3 (LGALS3) Antikörper (PE)
| Antigen | Lectin, Galactoside-Binding, Soluble, 3 (LGALS3) |
| Synonyme | GAL3, MAC2, CBP35, GALBP, GALIG, LGALS2, MGC52947, MGC75803, LGALS3, MGC151898, galectin-3, Galectin-3, MGC148757, leg3 |
| Klonalität | Monoklonal (Gal397) |
| Wirt |
 Alternativen Maus |
| Reaktivität |
Alternativen Maus, Human |
| Konjugat |
Alternativen PE |
| Applikation |
Alternativen Durchflusszytometrie (FACS)
|
| Produktnummer | ABIN313113 |
| Menge | 200 ug (Varianten) |
| Preis | 337,14 € Zzgl. Versandkosten €20,00 und MWSt |
| Lieferung nach |
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| Verfügbarkeit | Lieferung in 5 bis 7 Werktagen |
Produktbeschreibung
| Weitere Bezeichnung | Mac-2 (Galectin-3) |
| Immunogen | Recombinant (partial), amino acids 151-251 |
| Isotyp | IgG1, kappa chain |
| Klon | Gal397 |
| Beschreibung | Galectin-3 (galactose-specific lectin 3) is a 30-32 kD glycoprotein, also know as Mac-2, Gal-3, RL-29,galactose-specific lectin 3, CBP-35, L-34, and epsilonBP. It is a member of animal beta-galactoside-binding protein family thatis expressed in cell nucleus, cytoplasm, plasma membrane, or extracellular matrix by variety of tumor cells,monocytes/macrophages, epithelial cells, Kupffer cells, and dendritic cells. Galectin-3contains carbohydraterecognition domains and binds to beta-galactoside residues bearing glycoproteins, such as as IgE, IgA, galactose,casein kinase I, laminin, mucin, LAMPs, and CD66. Galectin-3 is an adhesion molecule and plays an important role inregulation of cell proliferation, differentiation and tumor cell metastasis. Galectin-3 structurely possesses NWGR motifthat is conserved in BH-1 domain of BCL-2 family and functions as an anti-apoptotic molecule. |
Anwendungen
| Applikationshinweise | Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For immunofluorescent staining, the suggested use of this reagent is approx. 0.25 ug per 106 cells in 100 ul volume. It isrecommended that the reagent be titrated for optimal performance for each application. |
| Reinigung | The antibody was purified by affinity chromatography, and conjugated withPE under optimal conditions. The solution is free of unconjugated PE andunconjugated antibody. |
| Buffer | Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide and0.2% (w/v) BSA (origin USA). |
| Lagerung | The antibody solution should be stored undiluted at 4 degrees C and protected from prolonged exposure to light. Do not freeze. |
| Beschränkungen | Nur für Forschungszwecke einsetzbar |
Alternativen
Alternativen zu Antigen "Lectin, Galactoside-Binding, Soluble, 3 (LGALS3)", Typ "Antikörper" finden
| Wirte | Kaninchen (25), Ratte (8), Maus (6) |
| Reaktivitäten | Human (37), Maus (37), Ratte (Rattus) (22), Rind (Kuh) (1), Hund (1), Pferd (1), Schwein (1), Kaninchen (1) |
| Applikationen | Durchflusszytometrie (FACS) (31), Immunfluoreszenz (IF) (21), Western Blot (WB) (12), Immunhistochemie (IHC) (8), ELISA (7), Immunpräzipitation (IP) (4), Immunhistochemie (formalinfixierte Schnitte) (IHC (f)) (2), Immunhistochemie (Paraffinschnitte) (IHC (p)) (2), Blockierende Antikörper (Inhibition) (1), Immunoelectron Microscopy (IEM) (1) |
| Konjugate | Biotin (5), PE (4), Alexa Fluor 647 (3), Alexa Flour 488 (1), Alexa Fluor 350 (1), Alexa Fluor 488 (1), Alexa Fluor 555 (1), Cy3 (1), Cy5 (1), Cy5.5 (1), Cy7 (1), FITC (1), Gold (1), HRP (1), PE,Cy3 (1), PE,Cy5 (1), PE,Cy5.5 (1), PE,Cy7 (1), RBITC (1) |
