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CD79b Molecule, Immunoglobulin-Associated beta (CD79B) Antikörper (PE)

Antigen

CD79b Molecule, Immunoglobulin-Associated beta (CD79B)

Synonyme B29, IGB, Igb, Igbeta, Ig-beta, MGC108607, CD79B, LOC100304995
Klonalität Monoklonal (HM79-12)
Wirt
Alternativen

Hamster

Reaktivität
Konjugat
Applikation
Alternativen Durchflusszytometrie (FACS)
Produktnummer ABIN313059
Menge 50 ug  (Varianten)
Preis 147,14 €   Zzgl. Versandkosten €20,00 und MWSt
Lieferung nach
Verfügbarkeit Lieferung in 5 bis 7 Werktagen

Produktbeschreibung

Weitere Bezeichnung CD79b
Isotyp IgG
Klon HM79-12
Beschreibung Mouse CD79b (Ig betachain) is a 35-40kDa transmembrane protein that forms aheterodimer with CD79a (30-35 kDa, Ig alpha chain). The CD79b and CD79ahererodimers are associated with surface IgM to form the B-cell receptor(BCR) that is necessary for signal transduction via the BCR in mature B cells. CD79b participates signal transduction involved in the development of Bcells as well. It was reported that association between CD79b/CD79a withIgM is essential in inducing both the transition from progenitor to precursor Bcells and subsequent allelic exclusion. Ig beta knockout mice had a completeblock in B cell development at the immature CD43+B220+ stage. TheHM79b-12 react with an extracellular epitope of CD79b or Ig beta.

Anwendungen

Applikationshinweise Each lot of this antibody is quality control tested by immunofluorescentstaining with flow cytometric analysis. For immunofluorescent staining, thesuggested use of this reagent is approx. 1.0 ug per 106 cells in 100 ul volume or100 ul of whole blood. It is recommended that the reagent be titrated foroptimal performance for each application.
Reinigung The antibody was purified by affinity chromatography, and conjugated withPE under optimal conditions. The solution is free of unconjugated PE andunconjugated antibody.
Buffer Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide.
Lagerung The antibody solution should be stored undiluted at 4 degrees C and protected from prolonged exposure to light. Do not freeze.
Beschränkungen Nur für Forschungszwecke einsetzbar

Alternativen

Alternativen zu Antigen "CD79b Molecule, Immunoglobulin-Associated beta (CD79B)", Typ "Antikörper" finden
Wirte Hamster (72), Maus (59), Ratte (9), Kaninchen (3)
Reaktivitäten Maus (73), Human (69), Hund (7), Ratte (Rattus) (6), Schwein (4)
Applikationen Durchflusszytometrie (FACS) (130), Western Blot (WB) (59), Immunpräzipitation (IP) (57), Immunhistochemie (Gefrierschnitte) (IHC (fro)) (37), Enzyme Immunoassay (EIA) (6), Immunfluoreszenz (IF) (6), Funktionale Studien (Func) (5), ELISA (Detektionsantikörper) (4), Immunhistochemie (IHC) (4), ELISA (2), Immunzytochemie (ICC) (2), Dot Blot (Dot) (1)
Konjugate FITC (33), PE (26), Biotin (11), RPE (5), APC (3), SPRD (2), Cy5,PE (1)