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Antikörper
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anti-Interleukin 2 Receptor, beta (IL2RB) Antikörper
Interleukin 2 Receptor, beta (IL2RB) Antikörper
| Antigen |
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| Synonyme |
CD122, P70-75, p70, IL15Rbeta, Il-2Rbeta, MGC118674, IL-15Rbeta, Il-2/15Rbeta, IL2RBC, IL2RB, il-2rb |
| Klonalität |
Monoklonal (TM-b1) |
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Wirt
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Reaktivität
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Applikation
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 Alternativen Blockierende Antikörper (Inhibition), Durchflusszytometrie (FACS), Immunpräzipitation (IP), Abreicherung (Depletion)
Durchflusszytometrie (FACS) (117), Immunpräzipitation (IP) (31), Western Blot (WB) (20), Funktionale Studien (Func) (9), ELISA (4), Immunfluoreszenz (IF) (4), ELISA (Detektionsantikörper) (3), Immunhistochemie (IHC) (2), Blockierende Antikörper (Inhibition) (1), Abreicherung (Depletion) (1), Dot Blot (Dot) (1), Immunhistochemie (Gefrierschnitte) (IHC (fro)) (1), Immunhistochemie (Paraffinschnitte) (IHC (p)) (1)
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| Produktnummer |
ABIN312656 |
| Menge |
500 ug (Varianten) |
| Preis |
337,14 € Zzgl. Versandkosten €20,00 und MWSt
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| Lieferung nach |
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| Verfügbarkeit |
Lieferung in 5 bis 7 Werktagen |
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Weitere Bezeichnung
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CD122
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Immunogen
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Rat T cell line expressing mouse CD122 ( IL-2Rbeta)
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Isotyp
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IgG2b, kappa chain (Passende Sekundärantikörper)
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Klon
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TM-b1
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Beschreibung
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CD122 is a 70-75 kD IL-2 receptor beta chain also known as IL-2Rbeta, which is also shared by the IL-15 receptor. It isconstitutively expressed by NK cells and at lower levels by T cells, B cells, monocytes, and macrophages. The IL-2Rbetachain can combine with either the common gamma subunit (gammac, CD132) alone or with the gammac subunit and the IL-2Ralpha subunit(CD25) to generate intermediate or high affinity IL-2 receptor complexes, respectively. CD122 expression levels canbe upregulated by activation. The TM-beta1 antibody does inhibit IL-2 binding to the IL-2 receptor.
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Applikationshinweise
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Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For immunofluorescent staining, the suggested use of this reagent is approx 0.25 ug per 106 cells in 100 ul volume. It isrecommended that the reagent be titrated for optimal performance for each application. Additional reported applications (for the relevant formats) include: immunoprecipitation1, blocking of IL-2 binding1, andNK cell depletion2 in vivo. The LEAF
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Reinheit
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LEAF Purified
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Reinigung
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The antibody was purified by affinity chromatography.
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Buffer
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Phosphate-buffered solution, pH 7.2, containing no preservative. 0.2 um filtersterilized. Endotoxin level is < 0.1 EU/ug of the protein (< 0.01 ng/ug of theprotein) as determined by the LAL test.
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Lagerung
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The antibody solution should be stored undiluted at 4 degrees C.
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Beschränkungen
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Nur für Forschungszwecke einsetzbar
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Alternativen zu Antigen "Interleukin 2 Receptor, beta (IL2RB)", Typ "Antikörper" finden
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Wirte
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Ratte (83), Maus (28), Kaninchen (16)
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Reaktivitäten
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Maus (90), Human (34), Ratte (Rattus) (28)
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Applikationen
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Durchflusszytometrie (FACS) (117), Immunpräzipitation (IP) (31), Western Blot (WB) (20), Funktionale Studien (Func) (9), ELISA (4), Immunfluoreszenz (IF) (4), ELISA (Detektionsantikörper) (3), Immunhistochemie (IHC) (2), Blockierende Antikörper (Inhibition) (1), Abreicherung (Depletion) (1), Dot Blot (Dot) (1), Immunhistochemie (Gefrierschnitte) (IHC (fro)) (1), Immunhistochemie (Paraffinschnitte) (IHC (p)) (1)
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Konjugate
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PE (23), Biotin (20), FITC (19), APC (5), RPE (1)
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Epitope
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Ab-364 (2), pTyr364 (2)
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