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Chemokine (C-X-C Motif) Receptor 7 (CXCR7) Antikörper (Biotin)

Antigen

Chemokine (C-X-C Motif) Receptor 7 (CXCR7)

Synonyme 5HT1a, 5-HT1A, ADRBRL1, ADRB2RL1, RDC1, CMKOR1, GPR159, anon-WO0170980.16, anon-WO0170980.17, anon-WO0170981.1, BEST:LD12308, CG3171, DmelCG3171, LD12308, sctt, tre-1, Tre-1, tre1
Klonalität Monoklonal (8F11-M16)
Wirt
Reaktivität
Alternativen

Human, Maus

Konjugat
Alternativen Biotin
Applikation
Alternativen Durchflusszytometrie (FACS)
Produktnummer ABIN312319
Menge 25 ug  (Varianten)
Preis 147,14 €   Zzgl. Versandkosten €20,00 und MWSt
Lieferung nach
Verfügbarkeit Lieferung in 5 bis 7 Werktagen

Produktbeschreibung

Weitere Bezeichnung CXCR7
Immunogen human CXCR7 transfectant
Isotyp IgG2b, kappa chain
Klon 8F11-M16
Beschreibung CXCR7, also known as RDC1, belongs to a subgroup of C-X-C chemokine receptors, which are part of a large proteinfamily of G protein-coupled receptors (GPCR). CXCR7 binds with high-affinity to CXCL12/SDF-1 and CXCL11/I-TAC,which regulates the trafficking and activation of leukocytes. It is also a co-receptor for the entry of HIV-1. Binding ofligand to CXCR7 induces proliferation and migration of immature neurons, glia and their precursors. CXCR7expression occurs on a wide variety of tissues and cells including monocytes, B cells, T cells and mature dendriticcells. Surface expression of CXCR7 was also reported to be on tumor cells, activated endothelial cells, fetal livercells, and few other cell types.

Anwendungen

Applikationshinweise Each lot of this antibody is quality control tested by immunofluorescentstaining with flow cytometric analysis. For immunofluorescent staining, thesuggested use of this reagent is approx. 2.0 ug per 106 cells in 100 ul volume or100 ul of whole blood. It is recommended that the reagent be titrated foroptimal performance for each application.
Reinigung The antibody was purified by affinity chromatography, and conjugated withbiotin under optimal conditions. The solution is free of unconjugated biotin.
Buffer Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide.
Lagerung The antibody solution should be stored undiluted at 4 degrees C. Do not freeze.
Beschränkungen Nur für Forschungszwecke einsetzbar

Alternativen

Alternativen zu Antigen "Chemokine (C-X-C Motif) Receptor 7 (CXCR7)", Typ "Antikörper" finden
Wirte Kaninchen (31), Maus (13)
Reaktivitäten Human (43), Maus (32), Ratte (Rattus) (23), Rind (Kuh) (17), Huhn (16), Kaninchen (15), Pferd (2), Affe (2), Schimpanse (1), Xenopus laevis (1)
Applikationen Immunfluoreszenz (IF) (21), Durchflusszytometrie (FACS) (14), Western Blot (WB) (12), Immunhistochemie (Paraffinschnitte) (IHC (p)) (6), Enzyme Immunoassay (EIA) (3), Immunhistochemie (Gefrierschnitte) (IHC (fro)) (3), Immunhistochemie (IHC) (3), ELISA (2), Immunhistochemie (formalinfixierte Schnitte) (IHC (f)) (2), Immunpräzipitation (IP) (2), Immunoelectron Microscopy (IEM) (1)
Konjugate PE (4), Biotin (2), APC (1), Alexa Flour 488 (1), Alexa Fluor 350 (1), Alexa Fluor 488 (1), Alexa Fluor 555 (1), Alexa Fluor 647 (1), CF (1), Cy3 (1), Cy5 (1), Cy5.5 (1), Cy7 (1), FITC (1), Gold (1), HRP (1), PE,Cy3 (1), PE,Cy5 (1), PE,Cy5.5 (1), PE,Cy7 (1), RBITC (1)
Epitope C-Term (2), N-Term (1)