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Toll-Like Receptor 1 (TLR1) Antikörper (Biotin)

Antigen

Toll-Like Receptor 1 (TLR1)

Synonyme TIL, CD281, rsc786, KIAA0012, MGC104956, MGC126311, MGC126312, DKFZp547I0610, DKFZp564I0682
Klonalität Monoklonal (TLR1-136)
Wirt
Reaktivität
Alternativen

Human

Konjugat
Alternativen Biotin
Applikation
Alternativen Durchflusszytometrie (FACS)
Produktnummer ABIN312186
Menge 25 ug  (Varianten)
Preis 128,57 €   Zzgl. Versandkosten €20,00 und MWSt
Lieferung nach
Verfügbarkeit Lieferung in 5 bis 7 Werktagen

Produktbeschreibung

Weitere Bezeichnung CD281 (TLR1)
Immunogen Human TLR1 transfected Ba/F3
Isotyp IgG1, kappa chain
Klon TLR1-136
Beschreibung Toll-like receptors (TLRs) are type I transmembrane signaling receptors characterized by containing leucine-richrepeats (LRR) extracellular domain and IL-1 receptor like intracellular domain. TLRs are responsible for recognizingpathogen-associated molecule patterns (PAMPs). They are primary sensors of both innate and adaptive immunesystems. To date a total of 12 TLRs have been indentified. Toll-like receptor 1 (TLR1), known as CD281, is expressedon monocytes/macrophages, dendritic cells, and granulocytes and some lymphocytes at low levels. By associationwith TLR2, TLR1 is a coreceptor involved in the response to diverse set of pathogens, such as triacylatedlipopeptidess (but not diacylated lipopeptides), peptidoglycans, lipoteichoic acid.

Anwendungen

Applikationshinweise Each lot of this antibody is quality control tested by immunofluorescentstaining with flow cytometric analysis. For immunofluorescent staining, thesuggested use of this reagent is approx. 2.0 ug per 106 cells in 100 ul volume. It isrecommended that the reagent be titrated for optimal performance for eachapplication. Other reported applications include immunoprecipitation1
Reinigung The antibody was purified by affinity chromatography, and conjugated withbiotin under optimal conditions. The solution is free of unconjugated biotinand unconjugated antibody.
Buffer Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide.
Lagerung The antibody solution should be stored undiluted at 4 degrees C. Do not freeze.
Beschränkungen Nur für Forschungszwecke einsetzbar

Alternativen

Alternativen zu Antigen "Toll-Like Receptor 1 (TLR1)", Typ "Antikörper" finden
Wirte Kaninchen (51), Maus (38), Ziege (6), Ratte (5)
Reaktivitäten Human (88), Maus (41), Ratte (Rattus) (23), Rind (Kuh) (16), Hund (16), Pferd (16)
Applikationen Durchflusszytometrie (FACS) (67), Western Blot (WB) (38), Immunfluoreszenz (IF) (20), Enzyme Immunoassay (EIA) (11), Immunhistochemie (Paraffinschnitte) (IHC (p)) (10), ELISA (6), Immunhistochemie (Gefrierschnitte) (IHC (fro)) (6), Immunhistochemie (IHC) (4), Immunpräzipitation (IP) (4), Immunhistochemie (formalinfixierte Schnitte) (IHC (f)) (2), Dot Blot (Dot) (1), Funktionale Studien (Func) (1), Immunoelectron Microscopy (IEM) (1)
Konjugate PE (10), Biotin (9), FITC (3), Alexa Fluor 488 (2), Alexa Fluor 647 (2), Alexa Flour 488 (1), Alexa Fluor 350 (1), Alexa Fluor 555 (1), Cy3 (1), Cy5 (1), Cy5.5 (1), Cy7 (1), Gold (1), HRP (1), PE,Cy3 (1), PE,Cy5 (1), PE,Cy5.5 (1), PE,Cy7 (1), RBITC (1), RPE (1)
Epitope N-Term (6), AA 400-450 (2), internal (1)