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Integrin beta 3 (ITGB3) Antikörper (Alexa Fluor 647)

Antigen

Integrin beta 3 (ITGB3)
Synonyme LAD, CD18, MF17, MFI7, LCAMB, LFA-1, MAC-1, CD61, GP3A, GPIIIa, INGRB3, MGC159221, MGC159223, integrin, ITGB3
Klonalität Monoklonal (VI-PL2)
Wirt
Reaktivität
Alternativen

Human
Konjugat
Alternativen Alexa Fluor 647
Applikation
Alternativen Durchflusszytometrie (FACS)
Produktnummer ABIN311867
Menge 25 tests  (Varianten)
Preis 147,14 €   Zzgl. Versandkosten €20,00 und MWSt
Lieferung nach
Verfügbarkeit Lieferung in 5 bis 7 Werktagen

Produktbeschreibung
Anwendungen Alternativen Varianten zurück nach oben

Weitere Bezeichnung CD61
Isotyp IgG1, kappa chain
Klon VI-PL2
Beschreibung Normal 0 false false false EN-US X-NONE X-NONE MicrosoftInternetExplorer4 /* Style Definitions */ table.MsoNormalTable {mso-style-name:"Table Normal", mso-tstyle-rowband-size:0, mso-tstyle-colband-size:0,mso-style-noshow:yes, mso-style-priority:99, mso-style-qformat:yes, mso-style-parent:"", mso-padding-alt:0in 5.4pt0in 5.4pt, mso-para-margin:0in, mso-para-margin-bottom:.0001pt, mso-pagination:widow-orphan, font-size:11.0pt,font-family:"Calibri","sans-serif", mso-ascii-font-family:Calibri, mso-ascii-theme-font:minor-latin,mso-fareast-font-family:"Times New Roman", mso-fareast-theme-font:minor-fareast, mso-hansi-font-family:Calibri,mso-hansi-theme-font:minor-latin, mso-bidi-font-family:"Times New Roman", mso-bidi-theme-font:minor-bidi,} CD61, known as integrin b3 or glycoprotein IIIa (gpIIIa), is a 90 kD type I integral transmembrane glycoprotein. It is amember of integrin family that associates with platelet gpIIb (CD41) forming CD41/CD61 complex and associates withintegrin aV (CD51) forming aV/b3 (CD51/CD61) integrin. CD41/CD61 is expressed on platelets and megakaryocytes,and plays a role in platelet activation and aggregation through interaction with fibrinogen, fibronectin, vWF and otherRGD-containing adhesion molecules. CD51/CD61 is expressed on platelets, osteoclasts, fibroblast, macrophagesand some tumor cells, involved in tumor metastasis and in adenovirus infection through binding to RGD motif ECMproteins.

Anwendungen
Alternativen Varianten zurück nach oben

Applikationshinweise Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For immunofluorescent staining, the suggested use of this reagent is 5 ul per million cells in 100 ul volume or 5 ul per 100ul of whole blood. It is recommended that the reagent be titrated for optimal performance for each application.* Alexa Fluor
Reinigung The antibody was purified by affinity chromatography, and conjugated withAlexa Fluor 647 under optimal conditions. The solution is free of unconjugated Alexa Fluor 647.
Buffer Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide and0.2% (w/v) BSA (origin USA).
Lagerung The antibody solution should be stored undiluted at 4 degrees C and protected from prolonged exposure to light. Do not freeze.
Beschränkungen Nur für Forschungszwecke einsetzbar

Alternativen
Anwendungen Varianten zurück nach oben

Alternativen zu Antigen "Integrin beta 3 (ITGB3)", Typ "Antikörper" finden
Wirte Maus (84), Kaninchen (62), Hamster (37), Huhn (1), Ratte (1)
Reaktivitäten Human (137), Maus (84), Ratte (Rattus) (49), Affe (10), Schwein (4), Huhn (2), Rind (Kuh) (2), Hund (2), Pferd (2), Primate (2), Hamster (1), Xenopus laevis (1)
Applikationen Durchflusszytometrie (FACS) (105), Western Blot (WB) (75), Immunhistochemie (Gefrierschnitte) (IHC (fro)) (39), Immunhistochemie (Paraffinschnitte) (IHC (p)) (27), Immunpräzipitation (IP) (22), Immunhistochemie (IHC) (20), ELISA (5), Enzyme Immunoassay (EIA) (5), Immunfluoreszenz (IF) (4), Aktivierung (Act) (2), Blockierende Antikörper (Inhibition) (2), Funktionale Studien (Func) (1)
Konjugate FITC (29), PE (18), Biotin (12), Alexa Fluor 647 (3), RPE (3), Alexa Fluor 488 (2), APC (1)
Epitope pTyr785 (11), pTyr773 (10), Ab-773 (5), Ab-785 (5), N-Term (1)