»
Antikörper
»
anti-Kinase insert Domain Receptor (A Type III Receptor tyrosine Kinase) (KDR) Ant...
Kinase insert Domain Receptor (A Type III Receptor tyrosine Kinase) (KDR) Antikörper (Alexa Fluor 647)
| Antigen |
|
| Synonyme |
Flk1, Ly73, Flk-1, Krd-1, VEGFR2, VEGFR-2, sVEGFR-2, 6130401C07, FLK1, CD309, VEGFR, Vegfr-2, MGC93590, KDR, FLK-1, flk-1, vegfr-2 |
| Klonalität |
Polyklonal |
|
Wirt
|
|
|
Reaktivität
|
|
|
Konjugat
|
|
|
Applikation
|
Western Blot (WB) (147), Immunhistochemie (Paraffinschnitte) (IHC (p)) (65), Immunfluoreszenz (IF) (59), Immunhistochemie (IHC) (54), Enzyme Immunoassay (EIA) (43), Immunhistochemie (Gefrierschnitte) (IHC (fro)) (26), Immunpräzipitation (IP) (20), Durchflusszytometrie (FACS) (19), ELISA (16), Funktionale Studien (Func) (4), Dot Blot (Dot) (1), Neutralisierung (Neut) (1)
|
| Produktnummer |
ABIN311850 |
| Menge |
25 tests |
| Preis |
152,86 € Zzgl. Versandkosten €20,00 und MWSt
|
| Lieferung nach |
|
| Verfügbarkeit |
Lieferung in 5 bis 7 Werktagen |
|
Weitere Bezeichnung
|
CD309 (VEGFR2)
|
|
Isotyp
|
IgG1, kappa chain
|
|
Klon
|
HKDR-1
|
|
Beschreibung
|
VEGF-R2, known as KDR, CD309, and Flk-1 (mouse), is a type I transmembrane glycoprotein. It is a member of theCSF-1/PDGF receptor family of type III tyrosine kinase receptors. Human VEGF-R2 is mainly expressed byendothelial cells, embryonic tissues, and megakaryocytes. It plays an important role in the regulation of angiogenesis,vasculogenesis and vascular permeability. The ligands of VEGF-R2 include VEGF-A, VEGF-C, VEGF-D, and VEGFsplice isoforms. Ligation of VEGF-R2 with it ligands results in the receptor dimerization and autophosphorylation,stimulating endothelial cell proliferation and migration.
|
|
Applikationshinweise
|
Each lot of this antibody is quality control tested by immunofluorescentstaining with flow cytometric analysis. For immunofluorescent staining, thesuggested use of this reagent is 5 ul per million cells or 5 ul per 100 ul ofwhole blood. It is recommended that the reagent be titrated for optimalperformance for each application.* Alexa Fluor
|
|
Reinigung
|
The antibody was conjugated with Alexa Fluor 647 under optimalconditions, and is at >85% purity. The solution is free of unconjugated AlexaFluor 647.
|
|
Buffer
|
Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide and0.2% (w/v) BSA (origin USA).
|
|
Lagerung
|
The antibody solution should be stored undiluted at 4 degrees C and protected from prolonged exposure to light. Do not freeze.
|
|
Beschränkungen
|
Nur für Forschungszwecke einsetzbar
|
Alternativen zu Antigen "Kinase insert Domain Receptor (A Type III Receptor tyrosine Kinase) (KDR)", Typ "Antikörper" finden
|
Wirte
|
Kaninchen (174), Maus (28), Ratte (3), Huhn (2), Escherichia Coli (E. coli) (1), Ziege (1)
|
|
Reaktivitäten
|
Human (192), Maus (114), Ratte (Rattus) (90), Hund (2)
|
|
Applikationen
|
Western Blot (WB) (147), Immunhistochemie (Paraffinschnitte) (IHC (p)) (65), Immunfluoreszenz (IF) (59), Immunhistochemie (IHC) (54), Enzyme Immunoassay (EIA) (43), Immunhistochemie (Gefrierschnitte) (IHC (fro)) (26), Immunpräzipitation (IP) (20), Durchflusszytometrie (FACS) (19), ELISA (16), Funktionale Studien (Func) (4), Dot Blot (Dot) (1), Neutralisierung (Neut) (1)
|
|
Konjugate
|
Biotin (11), HRP (2), PerCP,Cy5.5 (1)
|
|
Epitope
|
pTyr951 (11), pTyr1175 (10), pTyr1214 (10), C-Term (6), Ab-1175 (5), Ab-1214 (5), Ab-951 (5), N-Term (3), pTyr1054 (2), pY1054 (2), Tyr1054 (1), Tyr1214 (1), Tyr951 (1), pTyr1059 (1), pTyr996 (1), pY951 (1), pY996 (1), pYpY1054/1059 (1)
|
Alternativen 
