» Antikörper » anti-Chemokine (C-C Motif) Receptor 7 (CCR7) Antikörper (Alexa Fluor 647)

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	+49 (0)241 95 163 153
	+49 (0)241 95 163 155

Chemokine (C-C Motif) Receptor 7 (CCR7) Antikörper (Alexa Fluor 647)

Antigen	Chemokine (C-C Motif) Receptor 7 (CCR7)
Synonyme	BLR2, EBI1, CD197, CDw197, CMKBR7, Ebi1h, Cdw197, Cmkbr7, MGC108519, CCR7, MGC165629, zgc:165629
Klonalität	Monoklonal (TG8-CCR7)
Wirt	Alternativen Maus Ratte (27), Kaninchen (19), Maus (5), Ziege (2)
Reaktivität	Alternativen Human Maus (35), Human (26), Ratte (Rattus) (6)
Konjugat	Alternativen Alexa Fluor 647 Biotin (5), PE (5), APC (3), PE,Cy7 (3), PerCP,Cy5.5 (3), Alexa Fluor 700 (2), Alexa Fluor 488 (1)
Applikation	Alternativen Durchflusszytometrie (FACS) Durchflusszytometrie (FACS) (33), Immunhistochemie (Paraffinschnitte) (IHC (p)) (16), Western Blot (WB) (10), Immunfluoreszenz (IF) (5), Immunhistochemie (Gefrierschnitte) (IHC (fro)) (5), Enzyme Immunoassay (EIA) (4), Immunpräzipitation (IP) (4), Funktionale Studien (Func) (1)

Produktnummer	ABIN311835
Menge	25 tests
Preis	165,71 € Zzgl. Versandkosten €20,00 und MWSt
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Verfügbarkeit	Lieferung in 5 bis 7 Werktagen

Produktbeschreibung
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Weitere Bezeichnung	CD197 (CCR7)
Isotyp	IgG2a, kappa chain
Klon	TG8-CCR7
Beschreibung	CCR7 is a chemokine receptor that binds CCL19 and CCL21 (1). CCR7 and its ligands link innate and adaptiveimmunity through their effects on interactions between T cells and dendritic cells. Naive T cells enter the lymph nodethrough high endothelial venules, which express CCL21. Dendritic cells and macrophages enter the lymph nodethrough afferent lymphatics. The encounter of T cells and dendritic cells in the T cell zone is CCR7-dependent (2). Inaddition, during immunological surveillance, B lymphocytes re-circulate between B-cell-rich compartments (follicles orB zones) in secondary lymphoid organs, surveying for antigen. After antigen binding, B cells move to the boundary ofB and T zones to interact with T-helper cells, this B cell migration is directed by CCR7 and its ligands. CCR7-positivecancer cell expression has been associated to lymph node metastasis.

Anwendungen
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Applikationshinweise	Each lot of this antibody is quality control tested by immunofluorescentstaining with flow cytometric analysis. For immunofluorescent staining, thesuggested use of this reagent is 5 ul per million cells or 5 ul per 100 ul ofwhole blood. It is recommended that the reagent be titrated for optimalperformance for each application.* Alexa Fluor
Reinigung	The antibody was purified by affinity chromatography, and conjugated withAlexa Fluor 647 under optimal conditions. The solution is free of unconjugated Alexa Fluor 647.
Buffer	Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide and0.2% (w/v) BSA (origin USA).
Lagerung	The antibody solution should be stored undiluted at 4 degrees C and protected from prolonged exposure to light. Do not freeze.
Beschränkungen	Nur für Forschungszwecke einsetzbar

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anti-Chemokine (C-C Motif) Receptor 7 (CCR7) antibody (Alexa Fluor 647)

Alternativen
Anwendungen Bilder zurück nach oben

Alternativen zu Antigen "Chemokine (C-C Motif) Receptor 7 (CCR7)", Typ "Antikörper" finden

Wirte	Ratte (27), Kaninchen (19), Maus (5), Ziege (2)
Reaktivitäten	Maus (35), Human (26), Ratte (Rattus) (6)
Applikationen	Durchflusszytometrie (FACS) (33), Immunhistochemie (Paraffinschnitte) (IHC (p)) (16), Western Blot (WB) (10), Immunfluoreszenz (IF) (5), Immunhistochemie (Gefrierschnitte) (IHC (fro)) (5), Enzyme Immunoassay (EIA) (4), Immunpräzipitation (IP) (4), Funktionale Studien (Func) (1)
Konjugate	Biotin (5), PE (5), APC (3), PE,Cy7 (3), PerCP,Cy5.5 (3), Alexa Fluor 700 (2), Alexa Fluor 488 (1)
Epitope	C-Term (1), N-Term (1)