Killer Cell Immunoglobulin-Like Receptor, Two Domains, Long Cytoplasmic Tail, 5A (KIR2DL5A) Antikörper (Alexa Fluor 647)

Antigen: Killer Cell Immunoglobulin-Like Receptor, Two Domains, Long Cytoplasmic Tail, 5A (KIR2DL5A)

Klonalität: Monoklonal (UP-R1)

Wirt: Maus

Reaktivität: Human

Konjugat: Alexa Fluor 647

Applikation: Durchflusszytometrie (FACS)

Produktnummer: ABIN311818

Produktbeschreibung

Weitere Bezeichnung: CD158f (KIR2DL5)

Immunogen: Human KIR2DL5-Ig fusion protein

Klon: UP-R1

Beschreibung: CD158 molecules, also known as KIRs (killer cell immunoglobulin-like receptors), are a family of transmembraneproteins with either two (KIR2D) or three (KIR3D) Ig-like extracellular domains. Some KIRs with long cytoplasmicdomains contain ITIMs and posses inhibitory functions and others with short cytoplasmic region lack ITIM and haveactivation functions. 14 polymorphic KIR genes have been reported in humans. CD158f is a 60 kDa glycoprotein with2 Ig-like extracellular domains and long cytoplasmic domains. Its expression is highly polymorphic betweenindividuals and mainly expressed on a subset of NK cells and a small population of T cells. HLA class I alleles are theligands of CD158f.

Anwendungen

Applikationshinweise: Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For immunofluorescent staining, the suggested use of this reagent is 5 ul per million cells or 5 ul per 100 ul of wholeblood. It is recommended that the reagent be titrated for optimal performance for each application.* Alexa Fluor

Reinigung: The antibody was purified by affinity chromatography, and conjugated with Alexa Fluor 647 under optimalconditions. The solution is free of unconjugated Alexa Fluor 647 and unconjugated antibody.

Buffer: Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide and 0.2% (w/v) BSA (origin USA).

Lagerung: The antibody solution should be stored undiluted at 4 degrees C and protected from prolonged exposure to light. Do notfreeze.

Beschränkungen: Nur für Forschungszwecke einsetzbar