p97/VCP Antikörper (Alexa Fluor 488)

Antigen: p97/VCP

Klonalität: Monoklonal (4G9)

Wirt: Maus

Reaktivität: Human

Konjugat: Alexa Fluor 488

Applikation: Immunfluoreszenz (IF)

Produktnummer: ABIN311806

Produktbeschreibung

Immunogen: Recombinant human valosin containing protein

Isotyp: IgG1, kappa chain

Klon: 4G9

Beschreibung: P97/VCP (valosin containing protein) belongs to the AAA ATPase family, predicted molecular weight 97 kD. VCP isassociated with a variety of cellular activities, including cell cycle control, membrane fusion after mitosis, regulatesspindle disassembly at the end of mitosis, nuclear trafficking and the ubiquitin-proteasome degradation pathway. Inmany instances, specific adaptor proteins with which VCP forms multiprotein complexes direct its role in a givenprocess. This protein is required for the fusion of ER and Golgi membranes. Clone 4G9 has been shown to be usefulfor western blotting, immunoprecipitation, and immunoflorence staining of human p97/VCP protein.

Anwendungen

Applikationshinweise: Each lot of this antibody is quality control tested by immunofluorescence staining. For immunofluorescencemicroscopy, suggested working dilution(s): Use a dilution range of 1~4 ug/ml. It is recommended that the reagent betitrated for optimal performance for each application. Description: p97/VCP (valosin containing protein) belongs to the AAA ATPase family, predicted molecular weight 97 kD. VCP isassociated with a variety of cellular activities, including cell cycle control, membrane fusion after mitosis, regulatesspindle disassembly at the end of mitosis, nuclear trafficking and the ubiquitin-proteasome degradation pathway. Inmany instances, specific adaptor proteins with which VCP forms multiprotein complexes direct its role in a givenprocess. This protein is required for the fusion of ER and Golgi membranes. Clone 4G9 has been shown to be usefulfor western blotting, immunoprecipitation, and immunoflorence staining of human p97/VCP protein.

Reinigung: The antibody was purified by affinity chromatography, and conjugated with Alexa Fluor 488 under optimalconditions. The solution is free of unconjugated Alexa Fluor 488.

Buffer: Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide.

Lagerung: The antibody solution should be stored undiluted at 4 degrees C and protected from prolonged exposure to light. Do notfreeze.

Beschränkungen: Nur für Forschungszwecke einsetzbar