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Histone H3 (pSer28) Antikörper (Alexa Fluor 488)

Antigen

Histone H3

Synonyme
H3t, H3.4, H3/g, H3FT, MGC126886, MGC126888, Hist1, H3.2-221, DmelCG31613, CG31613, h3.2, h3/m, h3f2, h3fm, hist1h3g, H3F3, H3.3A, H3F3B, MGC87782, MGC87783, H3.3B, H3F3A, h3f3a, MGC52829, MGC86731, M ... mehr anzeigen
Epitope
Alternativen

pSer28

Klonalität Polyklonal
Wirt
Reaktivität
Alternativen

Human

Konjugat
Alternativen Alexa Fluor 488
Applikation
Alternativen Durchflusszytometrie (FACS)
Produktnummer ABIN311804
Menge 25 tests
Preis 147,14 €   Zzgl. Versandkosten €20,00 und MWSt
Lieferung nach
Verfügbarkeit Lieferung in 5 bis 7 Werktagen

Produktbeschreibung

Weitere Bezeichnung Histone H3-Phosphorylated (Ser28)
Immunogen Synthetic peptide conjugated to KLH, corresponding to amino acids 23-35 of Human Histone H3.
Isotyp IgG2a, kappa chain
Klon HTA28
Beschreibung H3 is a core component of the nucleosome that serves to wrap and compact DNA into chromatin. Histones therefore,limit the accessibility of DNA, providing mechanisms for transcription regulation, DNA repair and replication andchromosomal stability. During mitosis, H3 is phosphorylated at serine 28. This phosphorylation coincides withchromosome condensation initiated at prophase and disappears at late anaphase. H3 has been demonstrated to bephosphorylated by the action of MLTK-alpha (mixed linage kinase-like mitogen activated protein triple kinase alpha) inresponse to ultraviolet B light and epidermal growth factor, as well as Aurora-B during mitosis.
Synonyme H3t, H3.4, H3/g, H3FT, MGC126886, MGC126888, Hist1, H3.2-221, DmelCG31613, CG31613, h3.2, h3/m, h3f2, h3fm, hist1h3g, H3F3, H3.3A, H3F3B, MGC87782, MGC87783, H3.3B, H3F3A, h3f3a, MGC52829, MGC86731, MGC165454, zgc:56193, zgc:86731, wu:fb58e10, FLJ35099, FLJ56780, FLJ56787, MGC131639, MGC89877, HIST1H3A

Anwendungen

Applikationshinweise Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For immunofluorescent staining, the suggested use of this reagent is 5 ul per million cells or 5 ul per 100 ul of wholeblood. It is recommended that the reagent be titrated for optimal performance for each application.* Alexa Fluor
Reinigung The antibody was purified by affinity chromatography, and conjugated with Alexa Fluor 488 under optimalconditions. The solution is free of unconjugated Alexa Fluor 488.
Buffer Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide.
Lagerung The antibody solution should be stored undiluted at 4 degrees C and protected from prolonged exposure to light. Do notfreeze.
Beschränkungen Nur für Forschungszwecke einsetzbar

Alternativen

Alternativen zu Antigen "Histone H3", Typ "Antikörper" finden
Wirte Kaninchen (160), Maus (19), Schaf (6), Ratte (4)
Reaktivitäten Human (179), Maus (91), Ratte (Rattus) (82), Rind (Kuh) (23), Schwein (19), Kaninchen (19), Fruchtfliege (Drosophila melanogaster) (18), Hund (7), Huhn (5), Pferd (3), Schaf (3), Xenopus laevis (2), Meerschweinchen (1), Hamster (1), Säugetiere (1), Tetrahymena (1), Hefe (Saccharomyces Cerevisiae) (1)
Applikationen Western Blot (WB) (126), Immunfluoreszenz (IF) (91), Durchflusszytometrie (FACS) (57), ELISA (43), Enzyme Immunoassay (EIA) (32), Dot Blot (Dot) (24), Immunhistochemie (IHC) (22), Chromatin-Immunopräzipitation (ChiP) (19), Immunhistochemie (Paraffinschnitte) (IHC (p)) (17), Immunpräzipitation (IP) (16), Immunzytochemie (ICC) (9), Immunhistochemie (Gefrierschnitte) (IHC (fro)) (6), Immunhistochemie (formalinfixierte Schnitte) (IHC (f)) (2), Immunoelectron Microscopy (IEM) (1)
Konjugate Alexa Fluor 488 (9), Alexa Fluor 647 (9), Alexa Fluor 350 (7), Alexa Fluor 555 (7), PE,Cy5.5 (7), Biotin (2), HRP (2), Agarose Beads (1), Alexa Flour 488 (1), Cy3 (1), Cy5 (1), Cy5.5 (1), Cy7 (1), FITC (1), Gold (1), PE (1), PE,Cy3 (1), PE,Cy5 (1), PE,Cy7 (1), RBITC (1)
Epitope pSer28 (27), pSer10 (26), pThr3 (14), pThr11 (6), 3meLys79 (2), Mono Methyl Lysine 4 (2), N-Term (2), Tri Methyl Lysine 4 (2), 2meArg17 (1), 2meLys27 (1), 2meLys27, 3meLys27 (1), 2meLys36 (1), 2meLys4 (1), 2meLys79 (1), 3meLys27 (1), 3meLys27, pSer10 (1), 3meLys4 (1), 3meLys9 (1), 3meLys9, pSer10 (1), Ab-23 (1), Ab-3 (1), Acetyl-Lys14 (1), Acetyl-Lys18 (1), Acetyl-Lys23 (1), Acetyl-Lys27 (1), Acetylated (1), Arg2 (1), acLys9 (1), acLys9, pSer10 (1), acetyl-Lys9 (1), meLys27 (1), meLys36 (1), meLys4 (1), meLys79 (1), meLys9 (1)