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Antikörper
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anti-Interleukin 17A (IL17A) Antikörper (Alexa Fluor 488)
Interleukin 17A (IL17A) Antikörper (Alexa Fluor 488)
| Antigen |
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| Synonyme |
IL17, CTLA8, IL-17, IL-17A, Il17, Ctla8, Ctla-8, IL17F, IL17A, ChIL-17 |
| Klonalität |
Monoklonal (BL168) |
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Wirt
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Reaktivität
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Konjugat
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Applikation
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Durchflusszytometrie (FACS) (57), Western Blot (WB) (31), ELISA (23), Enzyme Immunoassay (EIA) (23), Neutralisierung (Neut) (22), Intrazelluläre Durchflusszytometrie (ICFC) (17), ELISA (Detektionsantikörper) (12), ELISPOT (11), ELISA (Fangantikörper) (8), Immunhistochemie (Paraffinschnitte) (IHC (p)) (7), Funktionale Studien (Func) (5), ELISPOT (Fangantikörper) (2), ELISPOT (Detektionsantikörper) (2), Immunfluoreszenz (IF) (2), Immunhistochemie (IHC) (2), Dot Blot (Dot) (1), Immunhistochemie (Gefrierschnitte) (IHC (fro)) (1)
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| Produktnummer |
ABIN311783 |
| Menge |
25 tests (Varianten) |
| Preis |
184,29 € Zzgl. Versandkosten €20,00 und MWSt
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| Lieferung nach |
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| Verfügbarkeit |
Lieferung in 5 bis 7 Werktagen |
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Weitere Bezeichnung
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IL-17A
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Immunogen
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Recombinant full length human IL-17A
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Isotyp
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IgG1, kappa chain
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Klon
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BL168
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Beschreibung
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IL-17A is the founding member of the IL-17 family, a group of six structurally related pro-inflammatory cytokines.IL-17A, secreted by activated CD4+ Th17 cell subpopulation, elicits multiple biological activities on a variety of cellsincluding: the induction of IL-6, IL-8, G-CSF, and PGE2 production in epithelial, endothelial or fibroblasts, theenhancement of surface expression of ICAM-1 in fibroblasts, activation of NF-kappaB and costimulation of T cellproliferation. Recent studies demonstrated that, in mice, activated IL-17-secreting CD4+ helper T cells (Th17 cells)mediate an autoimmune arthritis that clinically and immunologically resembles rheumatoid arthritis (RA). HumanIL-17A shows 63%, 63% and 72% amino acid sequence identity to rat IL-17A, mouse IL-17A and a protein encodedby the ORF13 gene of herpesvirus Saimiri (HVS), respectively.
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Applikationshinweise
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Each lot of this antibody is quality control tested by immunofluorescentstaining with flow cytometric analysis. For immunofluorescent staining, thesuggested use of this reagent is 5 ul per million cells or 5 ul per 100 ul ofwhole blood. It is recommended that the reagent be titrated for optimalperformance for each application.* Alexa Fluor
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Reinigung
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The antibody was purified by affinity chromatography, and conjugated withAlexa Fluor 488 under optimal conditions. The solution is free of unconjugated Alexa Fluor 488.
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Buffer
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Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide and0.2% (w/v) BSA (origin USA).
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Lagerung
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The antibody solution should be stored undiluted at 4 degrees C and protected from prolonged exposure to light. Do not freeze.
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Beschränkungen
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Nur für Forschungszwecke einsetzbar
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Alternativen zu Antigen "Interleukin 17A (IL17A)", Typ "Antikörper" finden
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Wirte
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Maus (87), Ratte (27), Kaninchen (17), Ziege (5), Huhn (1)
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Reaktivitäten
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Human (104), Maus (34), Ratte (Rattus) (3)
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Applikationen
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Durchflusszytometrie (FACS) (57), Western Blot (WB) (31), ELISA (23), Enzyme Immunoassay (EIA) (23), Neutralisierung (Neut) (22), Intrazelluläre Durchflusszytometrie (ICFC) (17), ELISA (Detektionsantikörper) (12), ELISPOT (11), ELISA (Fangantikörper) (8), Immunhistochemie (Paraffinschnitte) (IHC (p)) (7), Funktionale Studien (Func) (5), ELISPOT (Fangantikörper) (2), ELISPOT (Detektionsantikörper) (2), Immunfluoreszenz (IF) (2), Immunhistochemie (IHC) (2), Dot Blot (Dot) (1), Immunhistochemie (Gefrierschnitte) (IHC (fro)) (1)
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Konjugate
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Biotin (24), Alexa Fluor 647 (9), HRP (8), FITC (7), PE (7), PerCP,Cy5.5 (6), Alexa Fluor 488 (4), Pacific Blue (4), APC (1)
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Epitope
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N-Term (2), AA 20-155 (1), Center (1)
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Alternativen 
