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Antikörper
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anti-TEK Tyrosine Kinase, Endothelial (TEK) Antikörper (Alexa Fluor 488)
TEK Tyrosine Kinase, Endothelial (TEK) Antikörper (Alexa Fluor 488)
| Antigen |
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| Synonyme |
TIE2, VMCM, TIE-2, VMCM1, CD202B, MGC139569, TEK, DKFZp469E064 |
| Klonalität |
Monoklonal (33-1(Ab33)) |
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Wirt
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Reaktivität
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Konjugat
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Applikation
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Western Blot (WB) (37), Enzyme Immunoassay (EIA) (33), Durchflusszytometrie (FACS) (29), ELISA (3), Immunfluoreszenz (IF) (3), Immunhistochemie (Gefrierschnitte) (IHC (fro)) (3), Dot Blot (Dot) (2), Immunhistochemie (Paraffinschnitte) (IHC (p)) (2), Immunpräzipitation (IP) (2), Funktionale Studien (Func) (1), Immunhistochemie (IHC) (1), Neutralisierung (Neut) (1)
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| Produktnummer |
ABIN311778 |
| Menge |
25 tests (Varianten) |
| Preis |
147,14 € Zzgl. Versandkosten €20,00 und MWSt
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| Lieferung nach |
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| Verfügbarkeit |
Lieferung in 5 bis 7 Werktagen |
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Weitere Bezeichnung
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CD202b (Tie2/Tek)
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Immunogen
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Recombinant extracellular domain of human Tie2
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Isotyp
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IgG1, kappa chain
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Klon
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33-1(Ab33)
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Beschreibung
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CD202b is a 145 kD type I transmembrane protein, also known as Tie2 or TEK. It is a member of the receptortyrosine kinase (RTK) family of proteins and is expressed by endothelial cells and their progenitors, quiescenthematopoietic stem cells (HSCs), and a subpopulation of monocytes. Angiopoietin-1 (Ang-1) is an activator ofCD202b to promote, maintain, and stabilize mature vessels and to maintain HSCs in quiescent state. Ang-2 is anotherligand of CD202b, which is involved in postnatal angiogenesis and in antagonizing the effects of Ang-1. Tie2 binds toAng-4 as well.
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Applikationshinweise
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Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For immunofluorescent staining, the suggested use of this reagent is 5 ul per million cells or 5 ul per 100 ul of wholeblood. It is recommended that the reagent be titrated for optimal performance for each application.* Alexa Fluor
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Reinigung
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The antibody was purified by affinity chromatography, and conjugated withAlexa Fluor 488 under optimal conditions. The solution is free of unconjugated Alexa Fluor 488 and unconjugated antibody.
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Buffer
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Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide and0.2% (w/v) BSA (origin USA).
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Lagerung
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The antibody solution should be stored undiluted at 4 degrees C and protected from prolonged exposure to light. Do not freeze.
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Beschränkungen
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Nur für Forschungszwecke einsetzbar
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Alternativen zu Antigen "TEK Tyrosine Kinase, Endothelial (TEK)", Typ "Antikörper" finden
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Wirte
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Maus (35), Ratte (8), Kaninchen (6), Ziege (4)
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Reaktivitäten
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Human (46), Maus (9), Rind (Kuh) (1), Ratte (Rattus) (1)
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Applikationen
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Western Blot (WB) (37), Enzyme Immunoassay (EIA) (33), Durchflusszytometrie (FACS) (29), ELISA (3), Immunfluoreszenz (IF) (3), Immunhistochemie (Gefrierschnitte) (IHC (fro)) (3), Dot Blot (Dot) (2), Immunhistochemie (Paraffinschnitte) (IHC (p)) (2), Immunpräzipitation (IP) (2), Funktionale Studien (Func) (1), Immunhistochemie (IHC) (1), Neutralisierung (Neut) (1)
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Konjugate
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Biotin (10), PE (4), Alexa Fluor 647 (2), Alexa Fluor 488 (1)
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Epitope
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C-Term (2), N-Term (1), pTyr1113 (1), pTyr992 (1)
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Alternativen 
