DDOST Antikörper (N-Term)

Produktnummer ABIN310826

Produktdetails anti-DDOST Antikörper

Target: DDOST (Dolichyl-diphosphooligosaccharide--Protein Glycosyltransferase (DDOST))

Bindungsspezifität: N-Term

Reaktivität: Human, Maus, Ratte, Hund, Zebrafisch (Danio rerio), Kaninchen, Rind (Kuh), Schaf, Meerschweinchen, Pferd

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser DDOST Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Sequenz: SPSVEDFGGN INVETISAFI DGGGSVLVAA SSDIGDPLRE LGSECGIEFD

Homologie: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Sheep: 100%, Zebrafish: 100%

Produktmerkmale: This is a rabbit polyclonal antibody against DDOST. It was validated on Western Blot using a cell lysate as a positive control.

Aufreinigung: Protein A purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human DDOST

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator.

Kommentare:

Antigen size: 456 AA

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Details zu DDOST

Target: DDOST (Dolichyl-diphosphooligosaccharide--Protein Glycosyltransferase (DDOST))

Andere Bezeichnung: DDOST (DDOST Produkte)

Synonyme: AGER1 antikoerper, CDG1R antikoerper, OKSWcl45 antikoerper, OST antikoerper, OST48 antikoerper, WBP1 antikoerper, DDOST antikoerper, wu:fa11d01 antikoerper, zgc:66068 antikoerper, zgc:77478 antikoerper, Ddost antikoerper, CG9022 antikoerper, DmOST50 antikoerper, Dmel\\CG9022 antikoerper, DrOST antikoerper, OST48/WBP1 antikoerper, Ots48 antikoerper, anon-EST:Liang-1.11 antikoerper, clone 1.11 antikoerper, ost48 antikoerper, dolichyl-diphosphooligosaccharide--protein glycosyltransferase non-catalytic subunit antikoerper, dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit (non-catalytic) S homeolog antikoerper, dolichyl-diphosphooligosaccharide-protein glycosyltransferase antikoerper, dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit (non-catalytic) antikoerper, dolichyl-diphosphooligosaccharide--protein glycosyltransferase 48 kDa subunit antikoerper, dolichyl-di-phosphooligosaccharide-protein glycotransferase antikoerper, Oligosaccharyltransferase 48kD subunit antikoerper, DDOST antikoerper, ddost.S antikoerper, GTR26 antikoerper, ddost antikoerper, Ddost antikoerper, LOC5580056 antikoerper, PTRG_01946 antikoerper, Ost48 antikoerper

Hintergrund: DDOST is a component of the oligosaccharyltransferase complex which catalyzes the transfer of high-mannose oligosaccharides to asparagine residues on nascent polypeptides in the lumen of the rough endoplasmic reticulum. The protein complex co-purifies with ribosomes. DDOST is also implicated in the processing of advanced glycation endproducts (AGEs), which form from non-enzymatic reactions between sugars and proteins or lipids and are associated with aging and hyperglycemia.
Alias Symbols: AGE-R1, KIAA0115, MGC2191, OK/SW-cl.45, OST, OST48, WBP1, AGER1, OKSWcl45
Protein Interaction Partner: HUWE1, VAPB, UBC, FAF1, STAU1, ASB11, TRIM13, SUZ12, EED, CLN3, NXT1, SRSF11, FN1, ATF2, STT3B, MAGT1, ZMPSTE24, VDAC2, SSR4, SSR3, SLC25A3, ILF2, KRTCAP2, FBXO6, UBD, AMFR, AUP1, TMEM173, UNC93B1, MAPK6, HDAC5, AGO3, BRCC3, GSTK1, TMBIM4, PGRMC1, SAP18,
Protein Size: 456

Molekulargewicht: 46 kDa

Gen-ID: 1650

NCBI Accession: NM_005216, NP_005207

UniProt: Q5VWA5

Pathways: Cell RedoxHomeostasis