CDT1 Antikörper (C-Term)

Produktnummer ABIN310811

Produktdetails anti-CDT1 Antikörper

Target: CDT1 (Chromatin Licensing and DNA Replication Factor 1 (CDT1))

Bindungsspezifität: C-Term

Reaktivität: Human, Maus, Ratte, Schwein, Rind (Kuh), Hund, Kaninchen, Saccharomyces cerevisiae

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser CDT1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (IHC)

Sequenz: PATPPATPPA ASPSALKGVS QDLLERIRAK EAQKQLAQMT RCPEQEQRLQ

Homologie: Cow: 93%, Dog: 77%, Human: 100%, Mouse: 100%, Pig: 100%, Rabbit: 93%, Rat: 100%, Yeast: 85%

Produktmerkmale: This is a rabbit polyclonal antibody against CDT1. It was validated on Western Blot using a cell lysate as a positive control.

Aufreinigung: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the C terminal region of human CDT1

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator.

Kommentare:

Antigen size: 546 AA

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Details zu CDT1

Target: CDT1 (Chromatin Licensing and DNA Replication Factor 1 (CDT1))

Andere Bezeichnung: CDT1 (CDT1 Produkte)

Synonyme: CDT1 antikoerper, fc37h07 antikoerper, im:7158083 antikoerper, wu:fc37h07 antikoerper, wu:fi38h09 antikoerper, xcdt1 antikoerper, DUP antikoerper, RIS2 antikoerper, 2610318F11Rik antikoerper, AW545653 antikoerper, C76791 antikoerper, Ris2 antikoerper, dup antikoerper, ris2 antikoerper, chromatin licensing and DNA replication factor 1 antikoerper, chromatin licensing and DNA replication factor 1 L homeolog antikoerper, CDT1 antikoerper, cdt1 antikoerper, Cdt1 antikoerper, cdt1.L antikoerper

Hintergrund: CDT1 cooperates with CDC6 to promote the loading of the mini-chromosome maintenance complex onto chromatin to form the pre-replication complex necessary to initiate DNA replication. It binds DNA in a sequence-, strand-, and conformation-independent manner and is a potential oncogene.
Alias Symbols: DUP, RIS2
Protein Interaction Partner: FBXO31, SKP1, RBX1, CUL1, DTL, PCNA, HECW2, CDK2, CDC6, CDC5L, ORC2, ORC1, GMNN, DGCR8, UBC, SKP2, CDK1, CCNB1, CCNA2, FOXO3, DDB1, COPS5, CUL4A, CUL4B, SMARCA5, MCM6, MAPK8, MAPK1, HDAC11, KAT7, CCNA1, DDB2, CDK4, CCNE1, TP63, TP73, EP300, KAT2B, CDT1, U
Protein Size: 546

Molekulargewicht: 60 kDa

Gen-ID: 81620

NCBI Accession: NM_030928, NP_112190

UniProt: Q9H211

Pathways: MAPK Signalweg, Mitotic G1-G1/S Phases, DNA Replication, Synthesis of DNA