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NR1I3 Antikörper (N-Term)

NR1I3 Reaktivität: Human, Maus, Ratte, Hund, Meerschweinchen, Rind (Kuh), Schwein WB, IHC Wirt: Kaninchen Polyclonal unconjugated
Produktnummer ABIN310698
  • Target Alle NR1I3 Antikörper anzeigen
    NR1I3 (Nuclear Receptor Subfamily 1, Group I, Member 3 (NR1I3))
    Bindungsspezifität
    • 8
    • 8
    • 7
    • 6
    • 5
    • 5
    • 4
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    N-Term
    Reaktivität
    • 57
    • 22
    • 19
    • 8
    • 7
    • 6
    • 4
    • 3
    • 3
    • 2
    • 1
    • 1
    Human, Maus, Ratte, Hund, Meerschweinchen, Rind (Kuh), Schwein
    Wirt
    • 57
    • 5
    Kaninchen
    Klonalität
    • 61
    • 3
    Polyklonal
    Konjugat
    • 40
    • 6
    • 4
    • 4
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser NR1I3 Antikörper ist unkonjugiert
    Applikation
    • 50
    • 26
    • 17
    • 6
    • 3
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (IHC)
    Sequenz
    MASREDELRN CVVCGDQATG YHFNALTCEG CKGFFRRTVS KSIGPTCPFA
    Homologie
    Cow: 90%, Dog: 92%, Guinea Pig: 79%, Human: 100%, Mouse: 92%, Pig: 100%, Rat: 92%
    Produktmerkmale
    This is a rabbit polyclonal antibody against NR1I3. It was validated on Western Blot and immunohistochemistry.
    Aufreinigung
    Protein A purified
    Immunogen
    The immunogen is a synthetic peptide directed towards the N terminal region of human NR1I3
    Top Product
    Discover our top product NR1I3 Primärantikörper
  • Applikationshinweise
    Optimal working dilutions should be determined experimentally by the investigator.
    Kommentare

    Antigen size: 348 AA

    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Konzentration
    Lot specific
    Buffer
    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Handhabung
    Avoid repeated freeze-thaw cycles.
    Lagerung
    -20 °C
    Informationen zur Lagerung
    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • Target
    NR1I3 (Nuclear Receptor Subfamily 1, Group I, Member 3 (NR1I3))
    Andere Bezeichnung
    NR1I3 (NR1I3 Produkte)
    Synonyme
    AA209988 antikoerper, AI551208 antikoerper, CAR antikoerper, CAR-beta antikoerper, Care2 antikoerper, ESTM32 antikoerper, MB67 antikoerper, CAR1 antikoerper, CXR antikoerper, nuclear receptor subfamily 1 group I member 3 antikoerper, nuclear receptor subfamily 1, group I, member 3 antikoerper, NR1I3 antikoerper, Nr1i3 antikoerper
    Hintergrund
    NR1I3 mediates the induction of transcription of cytochrome P450 (CYP) genes by phenobarbital (PB) and PB-type inducers. NR1I3 activation induces hepatic expression of detoxification enzymes and transporters and increases liver size. NR1I3 can also regulate both liver homeostasis and tumorigenesis in response to xenobiotic stresses.
    Alias Symbols: CAR, CAR1, MB67, MGC150433, MGC97144, MGC97209
    Protein Interaction Partner: HSP90AA1, RXRA, CHD9, SNX13, SNRPD3, IGH, PSMC5, PSMC4, EIF3I, SRC, MAP4, FTH1, HNF4A, NR0B2, PPARGC1A, MED1, NCOA1, POU1F1,
    Protein Size: 348
    Molekulargewicht
    39 kDa
    Gen-ID
    9970
    NCBI Accession
    NM_005122, NP_005113
    UniProt
    Q5VTW5
    Pathways
    Nuclear Receptor Transcription Pathway, Intracellular Steroid Hormone Receptor Signaling Pathway, Steroid Hormone Mediated Signaling Pathway
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