LFNG Antikörper (N-Term)

Produktnummer ABIN310641

Produktdetails anti-LFNG Antikörper

Target: LFNG (LFNG O-Fucosylpeptide 3-beta-N-Acetylglucosaminyltransferase (LFNG))

Bindungsspezifität: N-Term

Reaktivität: Human, Maus, Ratte, Meerschweinchen, Rind (Kuh), Pferd, Saccharomyces cerevisiae

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser LFNG Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Sequenz: LSEYFSLLTR ARRDAGPPPG AAPRPADGHP RPLAEPLAPR DVFIAVKTTK

Homologie: Cow: 93%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rat: 100%, Yeast: 100%

Produktmerkmale: This is a rabbit polyclonal antibody against LFNG. It was validated on Western Blot using a cell lysate as a positive control.

Aufreinigung: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human LFNG

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator.

Kommentare:

Antigen size: 361 AA

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Details zu LFNG

Target: LFNG (LFNG O-Fucosylpeptide 3-beta-N-Acetylglucosaminyltransferase (LFNG))

Andere Bezeichnung: LFNG (LFNG Produkte)

Synonyme: SCDO3 antikoerper, AW061165 antikoerper, id:ibd2614 antikoerper, id:ibd5029 antikoerper, id:ibd5138 antikoerper, l-fng antikoerper, wu:fc69h02 antikoerper, wu:fi34c01 antikoerper, LFNG O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase antikoerper, LFNG O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase S homeolog antikoerper, LFNG antikoerper, Lfng antikoerper, lfng.S antikoerper, lfng antikoerper

Hintergrund: LFNG is a member of the glycosyltransferase superfamily. It is a single-pass type II Golgi membrane protein that functions as a fucose-specific glycosyltransferase, adding an N-acetylglucosamine to the fucose residue of a group of signaling receptors involved in regulating cell fate decisions during development. Mutations in the gene that encodes this protein have been associated with autosomal recessive spondylocostal dysostosis 3. This gene encodes a member of the glycosyltransferase superfamily. The encoded protein is a single-pass type II Golgi membrane protein that functions as a fucose-specific glycosyltransferase, adding an N-acetylglucosamine to the fucose residue of a group of signaling receptors involved in regulating cell fate decisions during development. Mutations in this gene have been associated with autosomal recessive spondylocostal dysostosis 3. Alternatively spliced transcript variants that encode different isoforms have been described, however, not all variants have been fully characterized.
Alias Symbols: SCDO3
Protein Interaction Partner: APP, NOTCH2, NOTCH1,
Protein Size: 361

Molekulargewicht: 39 kDa

Gen-ID: 3955

NCBI Accession: NM_001040168, NP_001035258

Pathways: Notch Signalweg