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Retinal Outer Segment Membrane Protein 1 (ROM1) (Middle Region) Antikörper

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Antigen
Synonyme ROM1, ROM, ROSP1, RP7, TSPAN23, rds35, rom, rosp1, tspan23, M101156, Rgsc1156, Rom-1, Rosp1, Tspan23
Epitop
Middle Region
(3), (2), (1), (1), (1), (1), (1)
Reaktivität
Rind (Kuh), Human, Maus, Ratte (Rattus)
(25), (14), (13)
Wirt
Kaninchen
(20), (5)
Klonalität
Polyklonal
Konjugat
Unkonjugiert
(1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Applikation
Western Blot (WB)
(14), (11), (3), (3), (2), (2)
Pubmed 1 Publikation vorhanden
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Produkt-ID vom Hersteller Anmelden zum Anzeigen Neu
Menge 50 μg
Optionen
Lieferung nach Deutschland ( )
Verfügbarkeit Lieferung in 6 bis 8 Werktagen
Immunogen Synthetic peptide directed towards the middle region of human ROM1
Blocking Peptide Zu diesem Produkt passt das Blocking Peptide ABIN983115.
Sequenz NPHSPRPCLQ NRLSDSYAHP LFDPRQPNQN LWAQGCHEVL LEHLQDLAGT
Homologie Human : 100 %, Bovine : 90 %, Mouse : 90 %, Rat : 90 %
Produktmerkmale This is a rabbit polyclonal antibody against ROM1. It was validated on Western Blot using a cell lysate as a positive control.
Reinigung Affinity Purified
Andere Bezeichnung ROM1 (ROM1 Antibody Abstract)
Hintergrund ROM1 is an integral membrane protein found in the photoreceptor disk rim of the eye. It can form homodimers or can heterodimerize with another photoreceptor, retinal degeneration slow (RDS). It is essential for disk morphogenesis, and may also function as an adhesion molecule involved in the stabilization and compaction of outer segment disks or in the maintenance of the curvature of the rim. Certain defects in this gene have been associated with the degenerative eye disease retinitis pigmentosa.This gene is a member of a photoreceptor-specific gene family and encodes an integral membrane protein found in the photoreceptor disk rim of the eye. This protein can form homodimers or can heterodimerize with another photoreceptor, retinal degeneration slow (RDS). It is essential for disk morphogenesis, and may also function as an adhesion molecule involved in the stabilization and compaction of outer segment disks or in the maintenance of the curvature of the rim. Certain defects in this gene have been associated with the degenerative eye disease retinitis pigmentosa.
Molekulargewicht 37 kDa
Gen-ID 6094
NCBI Accession NP_000318, NM_000327
UniProt Q03395
Forschungsgebiet Neurology
Applikationshinweise Optimal working dilutions should be determined experimentally by the investigator.
Kommentare

Antigen size: 351 AA

Beschränkungen Nur für Forschungszwecke einsetzbar
Format Lyophilized
Rekonstitution Add 50 µL of distilled water.
Konzentration 1 mg/mL
Buffer PBS buffer with 2 % sucrose
Handhabung Avoid repeated freeze-thaw cycles.
Lagerung -20 °C
Informationen zur Lagerung For longer periods of storage, store at -20 °C
Bilder des Herstellers
Western Blot (WB) image for anti-Retinal Outer Segment Membrane Protein 1 (ROM1) (Middle Region) Antikörper (ABIN310578) anti-Retinal Outer Segment Membrane Protein 1 (ROM1) (Middle Region) antibody
Allgemeine Veröffentlichungen Taylor, Noguchi, Totoki et al.: "Human chromosome 11 DNA sequence and analysis including novel gene identification. ..." in: Nature, Vol. 440, Issue 7083, pp. 497-500, 2006 (PubMed).

Produktnummer ABIN310578
358,51 €
Zzgl. Versandkosten 20,00 € und MWSt

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