STEAP3 Antikörper (N-Term)
-
- Target Alle STEAP3 Antikörper anzeigen
- STEAP3 (STEAP Family Member 3, Metalloreductase (STEAP3))
-
Bindungsspezifität
- N-Term
-
Reaktivität
- Human, Maus, Ratte, Meerschweinchen, Rind (Kuh), Hund, Pferd, Kaninchen, Schwein
-
Wirt
- Kaninchen
-
Klonalität
- Polyklonal
-
Konjugat
- Dieser STEAP3 Antikörper ist unkonjugiert
-
Applikation
- Western Blotting (WB)
- Sequenz
- LVGSGFKVVV GSRNPKRTAR LFPSAAQVTF QEEAVSSPEV IFVAVFREHY
- Homologie
- Cow: 86%, Dog: 79%, Guinea Pig: 86%, Horse: 93%, Human: 100%, Mouse: 100%, Pig: 92%, Rabbit: 93%, Rat: 100%
- Produktmerkmale
- This is a rabbit polyclonal antibody against STEAP3. It was validated on Western Blot using a cell lysate as a positive control.
- Aufreinigung
- Protein A purified
- Immunogen
- The immunogen is a synthetic peptide directed towards the N terminal region of human STEAP3
- Top Product
- Discover our top product STEAP3 Primärantikörper
-
-
- Applikationshinweise
- Optimal working dilutions should be determined experimentally by the investigator.
- Kommentare
-
Antigen size: 488 AA
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
-
- Format
- Liquid
- Konzentration
- Lot specific
- Buffer
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
- Konservierungsmittel
- Sodium azide
- Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Handhabung
- Avoid repeated freeze-thaw cycles.
- Lagerung
- -20 °C
- Informationen zur Lagerung
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
-
- Target
- STEAP3 (STEAP Family Member 3, Metalloreductase (STEAP3))
- Andere Bezeichnung
- STEAP3 (STEAP3 Produkte)
- Synonyme
- STEAP3 antikoerper, 1010001D01Rik antikoerper, Tsap6 antikoerper, pHyde antikoerper, AHMIO2 antikoerper, STMP3 antikoerper, TSAP6 antikoerper, dudlin-2 antikoerper, STEAP3 metalloreductase antikoerper, STEAP family member 3 antikoerper, STEAP3 antikoerper, steap3 antikoerper, Steap3 antikoerper
- Hintergrund
-
AS an endosomal ferrireductase, STEAP3 is required for efficient transferrin-dependent iron uptake in erythroid cells. It participates in erythroid iron homeostasis by reducing Fe(3+) to Fe(2+) and can also reduce of Cu(2+) to Cu(1+), suggesting that it participates in copper homeostasis. STEAP3 uses NAD(+) as acceptor (By similarity). It may play a role downstream of p53/TP53 to interface apoptosis and cell cycle progression. STEAP3 is indirectly involved in exosome secretion by facilitating the secretion of proteins such as TCT
Alias Symbols: STMP3, TSAP6, dudlin-2
Protein Interaction Partner: UBC, SETD7, BAD, TPT1, BNIP3L, PKMYT1,
Protein Size: 488 - Molekulargewicht
- 54 kDa
- Gen-ID
- 55240
- NCBI Accession
- NM_001008410, NP_001008410
- UniProt
- Q658P3
- Pathways
- Transition Metal Ion Homeostasis
-