STEAP3 Antikörper (N-Term)

Produktnummer ABIN310477

Produktdetails anti-STEAP3 Antikörper

Target: STEAP3 (STEAP Family Member 3, Metalloreductase (STEAP3))

Bindungsspezifität: N-Term

Reaktivität: Human, Maus, Ratte, Meerschweinchen, Rind (Kuh), Hund, Pferd, Kaninchen, Schwein

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser STEAP3 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Sequenz: LVGSGFKVVV GSRNPKRTAR LFPSAAQVTF QEEAVSSPEV IFVAVFREHY

Homologie: Cow: 86%, Dog: 79%, Guinea Pig: 86%, Horse: 93%, Human: 100%, Mouse: 100%, Pig: 92%, Rabbit: 93%, Rat: 100%

Produktmerkmale: This is a rabbit polyclonal antibody against STEAP3. It was validated on Western Blot using a cell lysate as a positive control.

Aufreinigung: Protein A purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human STEAP3

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator.

Kommentare:

Antigen size: 488 AA

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Details zu STEAP3

Target: STEAP3 (STEAP Family Member 3, Metalloreductase (STEAP3))

Andere Bezeichnung: STEAP3 (STEAP3 Produkte)

Synonyme: STEAP3 antikoerper, 1010001D01Rik antikoerper, Tsap6 antikoerper, pHyde antikoerper, AHMIO2 antikoerper, STMP3 antikoerper, TSAP6 antikoerper, dudlin-2 antikoerper, STEAP3 metalloreductase antikoerper, STEAP family member 3 antikoerper, STEAP3 antikoerper, steap3 antikoerper, Steap3 antikoerper

Hintergrund: AS an endosomal ferrireductase, STEAP3 is required for efficient transferrin-dependent iron uptake in erythroid cells. It participates in erythroid iron homeostasis by reducing Fe(3+) to Fe(2+) and can also reduce of Cu(2+) to Cu(1+), suggesting that it participates in copper homeostasis. STEAP3 uses NAD(+) as acceptor (By similarity). It may play a role downstream of p53/TP53 to interface apoptosis and cell cycle progression. STEAP3 is indirectly involved in exosome secretion by facilitating the secretion of proteins such as TCT
Alias Symbols: STMP3, TSAP6, dudlin-2
Protein Interaction Partner: UBC, SETD7, BAD, TPT1, BNIP3L, PKMYT1,
Protein Size: 488

Molekulargewicht: 54 kDa

Gen-ID: 55240

NCBI Accession: NM_001008410, NP_001008410

UniProt: Q658P3

Pathways: Transition Metal Ion Homeostasis