AMFR Antikörper (C-Term)

Produktnummer ABIN310408

Produktdetails anti-AMFR Antikörper

Target: AMFR (Autocrine Motility Factor Receptor (AMFR))

Bindungsspezifität: C-Term

Reaktivität: Human, Maus, Ratte, Hund, Rind (Kuh), Meerschweinchen, Pferd, Kaninchen, Zebrafisch (Danio rerio)

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser AMFR Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Sequenz: FGEVEVEPSE VEDFEARGSR FSKSADERQR MLVQRKDELL QQARKRFLNK

Homologie: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 93%

Produktmerkmale: This is a rabbit polyclonal antibody against AMFR. It was validated on Western Blot using a cell lysate as a positive control.

Aufreinigung: Protein A purified

Immunogen: The immunogen is a synthetic peptide directed towards the C terminal region of human AMFR

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator.

Kommentare:

Antigen size: 482 AA

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Details zu AMFR

Target: AMFR (Autocrine Motility Factor Receptor (AMFR))

Andere Bezeichnung: AMFR (AMFR Produkte)

Synonyme: GP78 antikoerper, RNF45 antikoerper, gp78 antikoerper, wu:fi06e06 antikoerper, wu:fi37e05 antikoerper, zgc:63893 antikoerper, rnf45 antikoerper, autocrine motility factor receptor antikoerper, autocrine motility factor receptor L homeolog antikoerper, autocrine motility factor receptor a antikoerper, autocrine motility factor receptor, amfr antikoerper, putative autocrine motility factor receptor, amfr antikoerper, AMFR antikoerper, Amfr antikoerper, amfr.L antikoerper, amfra antikoerper, amfr antikoerper, AaeL_AAEL005881 antikoerper, CpipJ_CPIJ016043 antikoerper, Smp_047420 antikoerper

Hintergrund: Autocrine motility factor is a tumor motility-stimulating protein secreted by tumor cells. AMFR is a glycosylated transmembrane protein and a receptor for autocrine motility factor. The receptor, which shows some sequence similarity to tumor protein p53, is localized to the leading and trailing edges of carcinoma cells.The Makorin ring finger protein-1 gene (MKRN1) is a highly transcribed, intron-containing source for a family of intronless mammalian genes encoding a novel class of zinc finger proteins. Phylogenetic analyses indicate that the MKRN1 gene is the ancestral founder of this gene family (Gray et al., 2000).[supplied by OMIM].
Alias Symbols: GP78, RNF45
Protein Interaction Partner: VCP, UBE2G1, HSPA5, ERLIN2, INSIG1, HMGCR, DHFR, AMFR, UBE2D1, UBC, GPI, TRIM25, DGAT2, UBE2K, Ube2g2, NPLOC4, HERPUD1, BAG6, MAVS, YOD1, ADRA1D, DERL2, ADRB2, FAF2, SEC61B, RPN1, STT3A, STT3B, AUP1, MDC1, SNED1, DDOST, GET4, UBXN4, UBL4A, CD82, SARAF, IT
Protein Size: 643

Molekulargewicht: 73 kDa

Gen-ID: 267

NCBI Accession: NM_013446

UniProt: Q9UKV5

Pathways: ER-Nucleus Signaling