DLAT Antikörper (N-Term)

Produktnummer ABIN310264

Produktdetails anti-DLAT Antikörper

Target: DLAT (Dihydrolipoyl Transacetylase (DLAT))

Bindungsspezifität: N-Term

Reaktivität: Human, Maus, Ratte, Kaninchen, Hund, Zebrafisch (Danio rerio), Rind (Kuh), Meerschweinchen, Pferd

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser DLAT Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (IHC)

Sequenz: WTPSSGATPR NRLLLQLLGS PGRRYYSLPP HQKVPLPSLS PTMQAGTIAR

Homologie: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 86%

Produktmerkmale: This is a rabbit polyclonal antibody against DLAT. It was validated on Western Blot and immunohistochemistry.

Aufreinigung: Protein A purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human DLAT

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator.

Kommentare:

Antigen size: 647 AA

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Details zu DLAT

Target: DLAT (Dihydrolipoyl Transacetylase (DLAT))

Andere Bezeichnung: DLAT (DLAT Produkte)

Synonyme: DLAT antikoerper, Dmel\\CG5261 antikoerper, EP(2)0816 antikoerper, EP816 antikoerper, anon-WO0118547.121 antikoerper, DLTA antikoerper, PDC-E2 antikoerper, PDCE2 antikoerper, wu:fc14f10 antikoerper, wu:fc21f08 antikoerper, wu:fc86g11 antikoerper, wu:fj57d06 antikoerper, 6332404G05Rik antikoerper, midline uncoordinated antikoerper, dihydrolipoamide S-acetyltransferase L homeolog antikoerper, dihydrolipoamide S-acetyltransferase antikoerper, dihydrolipoamide S-acetyltransferase (E2 component of pyruvate dehydrogenase complex) antikoerper, muc antikoerper, dlat.L antikoerper, DLAT antikoerper, Dlat antikoerper, dlat antikoerper

Hintergrund: DLAT is dihydrolipoamide acetyltransferase, the E2 subunit of the mammalian pyruvate dehydrogenase complex of the inner mitochondrial membrane. Patients with primary biliary cirrhosis show autoantibodies to DLAT.The DLAT gene encodes dihydrolipoamide acetyltransferase (EC 2.3.1.12), the E2 subunit of the mammalian pyruvate dehydrogenase complex (PDC, EC 1.2.4.1) of the inner mitochondrial membrane. Patients with primary biliary cirrhosis (PBC, MIM 109720) show autoantibodies to DLAT.[supplied by OMIM].
Alias Symbols: DLTA, PDC-E2, PDCE2
Protein Interaction Partner: MDM2, UBC, ADRB2, PRKD3, PDHX, MMGT1, MRPL1, ACAD9, SYNCRIP, PDHA2, PDHA1, OGDH, NDUFS4, HSPA1L, DLD, COX5B, COPS5, CUL1, SIRT7, TSG101, KIAA0101, PSMA3, PDK4, PDK3, PDK2, PDK1, PDHB,
Protein Size: 647

Molekulargewicht: 69 kDa

Gen-ID: 1737

NCBI Accession: NM_001931, NP_001922

UniProt: P10515