LCAT Antikörper (N-Term)

Produktnummer ABIN310203

Produktdetails anti-LCAT Antikörper

Target: LCAT (Lecithin-Cholesterol Acyltransferase (LCAT))

Bindungsspezifität: N-Term

Reaktivität: Human, Maus, Ratte, Hund, Rind (Kuh), Kaninchen, Meerschweinchen, Schaf, Pferd

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser LCAT Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Sequenz: MGPPGSPWQW VTLLLGLLLP PAAPFWLLNV LFPPHTTPKA ELSNHTRPVI

Homologie: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Sheep: 100%

Produktmerkmale: This is a rabbit polyclonal antibody against LCAT. It was validated on Western Blot using a cell lysate as a positive control.

Aufreinigung: Protein A purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human LCAT

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator.

Kommentare:

Antigen size: 440 AA

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Referenzen für anti-LCAT Antikörper (ABIN310203)

Hirata, Yimin, Segawa, Ozaki, Kobayashi, Shigyo, Chiba: "Xanthohumol prevents atherosclerosis by reducing arterial cholesterol content via CETP and apolipoprotein E in CETP-transgenic mice." in: PLoS ONE, Vol. 7, Issue 11, pp. e49415, (2012) (PubMed).

Details zu LCAT

Target: LCAT (Lecithin-Cholesterol Acyltransferase (LCAT))

Andere Bezeichnung: LCAT (LCAT Produkte)

Synonyme: AI046659 antikoerper, D8Wsu61e antikoerper, MGC82035 antikoerper, lcat antikoerper, MGC88964 antikoerper, LCAT antikoerper, lecithin-cholesterol acyltransferase antikoerper, lecithin cholesterol acyltransferase antikoerper, lecithin-cholesterol acyltransferase L homeolog antikoerper, solute carrier family 12 member 4 antikoerper, fragile site, aphidicolin type, common, fra(13)(q13.2) antikoerper, LCAT antikoerper, Lcat antikoerper, lcat.L antikoerper, lcat antikoerper, SLC12A4 antikoerper, FRA13A antikoerper

Hintergrund: LCAT is an extracellular cholesterol esterifying enzyme, lecithin-cholesterol acyltransferase. The esterification of cholesterol is required for cholesterol transport. Mutations in its gene have been found to cause fish-eye disease as well as LCAT deficiency.This gene encodes the extracellular cholesterol esterifying enzyme, lecithin-cholesterol acyltransferase. The esterification of cholesterol is required for cholesterol transport. Mutations in this gene have been found to cause fish-eye disease as well as LCAT deficiency.
Protein Interaction Partner: APOA1, EXOSC10, APOE, APOA2, A2M,
Protein Size: 440

Molekulargewicht: 48 kDa

Gen-ID: 3931

NCBI Accession: NM_000229, NP_000220

UniProt: P04180

Pathways: Lipid Metabolism