CEACAM6 Antikörper (Middle Region)

Produktnummer ABIN310166

Produktdetails anti-CEACAM6 Antikörper

Target: CEACAM6 (Carcinoembryonic Antigen-Related Cell Adhesion Molecule 6 (CEACAM6))

Bindungsspezifität: Middle Region

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser CEACAM6 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (IHC)

Sequenz: EIQNPASANR SDPVTLNVLY GPDGPTISPS KANYRPGENL NLSCHAASNP

Homologie: Human: 100%

Produktmerkmale: This is a rabbit polyclonal antibody against CEACAM6. It was validated on Western Blot and immunohistochemistry.

Aufreinigung: Protein A purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human CEACAM6

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator.

Kommentare:

Antigen size: 344 AA

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Referenzen für anti-CEACAM6 Antikörper (ABIN310166)

Kobayashi, Miki, Ebina, Abe, Mori, Narumi, Suzuki, Sato, Maemondo, Endo, Inoue, Kumamoto, Kondo, Yamada-Okabe, Nukiwa, Sasano: "Carcinoembryonic antigen-related cell adhesion molecules as surrogate markers for EGFR inhibitor sensitivity in human lung adenocarcinoma." in: British journal of cancer, Vol. 107, Issue 10, pp. 1745-53, (2012) (PubMed).

Details zu CEACAM6

Target: CEACAM6 (Carcinoembryonic Antigen-Related Cell Adhesion Molecule 6 (CEACAM6))

Andere Bezeichnung: CEACAM6 (CEACAM6 Produkte)

Synonyme: CD66c antikoerper, CEAL antikoerper, NCA antikoerper, carcinoembryonic antigen-related cell adhesion molecule 6 antikoerper, carcinoembryonic antigen related cell adhesion molecule 6 antikoerper, Ceacam6 antikoerper, CEACAM6 antikoerper

Hintergrund: Many breast, pancreatic, colonic and non-small-cell lung carcinoma lines express CEACAM6 and CEACAM5, and antibodies to both can affect tumor cell growth in vitro and in vivo. CEACAM6 expression is elevated in many solid tumors, but variable as a function of histotype. It may be a promising target for antibody-based therapy.
Alias Symbols: CD66c, CEAL, NCA
Protein Interaction Partner: CARTPT, CEACAM6, CEACAM8, CEACAM7, CEACAM5, CEACAM1, APP,
Protein Size: 344

Molekulargewicht: 38 kDa

Gen-ID: 4680

NCBI Accession: NM_002483, NP_002474

UniProt: P40199