CPSF1 Antikörper (Middle Region)

Produktnummer ABIN310073

Produktdetails anti-CPSF1 Antikörper

Target: CPSF1 (Cleavage and Polyadenylation Specific Factor 1, 160kDa (CPSF1))

Bindungsspezifität: Middle Region

Reaktivität: Human, Ratte, Pferd

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser CPSF1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Sequenz: GCYDMWTVIA PVRKEEEDNP KGEGTEQEPS TTPEADDDGR RHGFLILSRE

Homologie: Horse: 79%, Human: 100%, Rat: 77%

Produktmerkmale: This is a rabbit polyclonal antibody against CPSF1. It was validated on Western Blot using a cell lysate as a positive control.

Aufreinigung: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human CPSF1

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator.

Kommentare:

Antigen size: 1443 AA

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Details zu CPSF1

Target: CPSF1 (Cleavage and Polyadenylation Specific Factor 1, 160kDa (CPSF1))

Andere Bezeichnung: CPSF1 (CPSF1 Produkte)

Synonyme: CG10110 antikoerper, CPSF antikoerper, CPSF-160 antikoerper, CPSF160 antikoerper, Cpsf antikoerper, Dmel\\CG10110 antikoerper, anon-WO0118547.217 antikoerper, cpsf antikoerper, dCPSF-160 antikoerper, wu:fb24c01 antikoerper, CPSF1 antikoerper, DKFZp469K0832 antikoerper, HSU37012 antikoerper, P/cl.18 antikoerper, ATCPSF160 antikoerper, K17N15.21 antikoerper, K17N15_21 antikoerper, cleavage and polyadenylation specificity factor 160 antikoerper, cleavage and polyadenylation specific factor 1 antikoerper, Cleavage and polyadenylation specificity factor 160 antikoerper, cleavage and polyadenylation specific factor 1 L homeolog antikoerper, cleavage and polyadenylation specificity factor subunit 1 antikoerper, cleavage and polyadenylation specificity factor 160 antikoerper, Cpsf1 antikoerper, Cpsf160 antikoerper, cpsf1.L antikoerper, cpsf1 antikoerper, CPSF1 antikoerper, Tsp_05366 antikoerper, CPSF160 antikoerper

Hintergrund: CPSF1 is a component of the cleavage and polyadenylation specificity factor (CPSF) complex that plays a key role in pre-mRNA 3'-end formation, recognizing the AAUAAA signal sequence and interacting with poly(A) polymerase and other factors to bring about cleavage and poly(A) addition. This subunit is involved in the RNA recognition step of the polyadenylation reaction.
Alias Symbols: CPSF160, HSU37012, P/cl.18
Protein Interaction Partner: REL, RBBP6, UBC, STAU1, LGR4, WWOX, RPA3, RPA2, RPA1, EED, EZH2, NEDD4, TARDBP, ICK, CLK2, HDAC6, NPM1, IL7R, HMOX1, TUT1, FIP1L1, RNPC3, WDR33, CPSF2, MED8, CPSF3, GTF3C3, POLR2A, COPS6, CUL3, SIRT7, SMARCAD1, CSTF2T, PAPOLA, CSTF3, GLIS2, RRAGA, TBP, TA
Protein Size: 1443

Molekulargewicht: 161 kDa

Gen-ID: 29894

NCBI Accession: NM_013291, NP_037423

UniProt: Q10570