SF3A3 Antikörper (Middle Region)

Produktnummer ABIN310069

Produktdetails anti-SF3A3 Antikörper

Target: SF3A3 (Splicing Factor 3a, Subunit 3, 60kDa (SF3A3))

Bindungsspezifität: Middle Region

Reaktivität: Human, Maus, Ratte, Zebrafisch (Danio rerio), Kaninchen, Rind (Kuh), Hund, Pferd, Meerschweinchen, Saccharomyces cerevisiae

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser SF3A3 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Sequenz: THENVQRKQA RTGEEREEEE EEQISESESE DEENEIIYNP KNLPLGWDGK

Homologie: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Yeast: 100%, Zebrafish: 91%

Produktmerkmale: This is a rabbit polyclonal antibody against SF3A3. It was validated on Western Blot using a cell lysate as a positive control.

Aufreinigung: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human SF3A3

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator.

Kommentare:

Antigen size: 501 AA

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Referenzen für anti-SF3A3 Antikörper (ABIN310069)

Ewing, Chu, Elisma, Li, Taylor, Climie, McBroom-Cerajewski, Robinson, OConnor, Li, Taylor, Dharsee, Ho, Heilbut, Moore, Zhang, Ornatsky, Bukhman, Ethier, Sheng, Vasilescu, Abu-Farha, Lambert, Duewel et al.: "Large-scale mapping of human protein-protein interactions by mass spectrometry. ..." in: Molecular systems biology, Vol. 3, pp. 89, (2007) (PubMed).

Details zu SF3A3

Target: SF3A3 (Splicing Factor 3a, Subunit 3, 60kDa (SF3A3))

Andere Bezeichnung: SF3A3 (SF3A3 Produkte)

Synonyme: PRP9 antikoerper, PRPF9 antikoerper, SAP61 antikoerper, SF3a60 antikoerper, 4930512K19Rik antikoerper, 60kDa antikoerper, LRRGT00093 antikoerper, wu:fi15a06 antikoerper, wu:fj94f01 antikoerper, zgc:110227 antikoerper, splicing factor 3a subunit 3 antikoerper, splicing factor 3a, subunit 3, 60kDa antikoerper, splicing factor 3a, subunit 3 antikoerper, splicing factor 3a subunit 3 S homeolog antikoerper, SF3A3 antikoerper, Sf3a3 antikoerper, sf3a3.S antikoerper, sf3a3 antikoerper

Hintergrund: SF3A3 is the subunit 3 of the splicing factor 3a protein complex. The splicing factor 3a heterotrimer includes subunits 1, 2 and 3 and is necessary for the in vitro conversion of 15S U2 snRNP into an active 17S particle that performs pre-mRNA splicing. Subunit 3 interacts with subunit 1 through its amino-terminus while the zinc finger domain of subunit 3 plays a role in its binding to the 15S U2 snRNP.This This gene encodes subunit 3 of the splicing factor 3a protein complex. The splicing factor 3a heterotrimer includes subunits 1, 2 and 3 and is necessary for the in vitro conversion of 15S U2 snRNP into an active 17S particle that performs pre-mRNA splicing. Subunit 3 interacts with subunit 1 through its amino-terminus while the zinc finger domain of subunit 3 plays a role in its binding to the 15S U2 snRNP. This gene has a pseudogene on chromosome 20. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
Alias Symbols: PRP9, PRPF9, SAP61, SF3a60
Protein Interaction Partner: TRIM69, HUWE1, ZNF212, TADA2A, FUS, UBC, NEDD8, MDM2, WWOX, RNF2, SUZ12, EED, rev, APBB1, ACTN1, ACTN4, STAM2, HGS, SNRPB, CDAN1, PRPF40A, WBP4, TCERG1, UBD, SF3A1, FN1, gag-pol, PRMT5, PRPF19, PRPF31, SF3B1, SF3B3, SF3B4, HNRNPR, DDX46, TOX4, DDX23, PRPF
Protein Size: 501

Molekulargewicht: 59 kDa

Gen-ID: 10946

NCBI Accession: NM_006802, NP_006793

UniProt: Q12874

Pathways: Ribonucleoprotein Complex Subunit Organization