»
Antikörper
»
anti-Neural Precursor Cell Expressed, Developmentally Down-Regulated 8 (NEDD8) Ant...
Neural Precursor Cell Expressed, Developmentally Down-Regulated 8 (NEDD8) Antikörper
| Antigen |
|
| Synonyme |
Nedd-8, FLJ43224, MGC104393, MGC125896, MGC125897, Rub1, MGC105320, CG10679, DmelCG10679, nedd8, ubiquitin, si:zc14a17.5, NEDD8, GB17785, LOC100009008 |
| Klonalität |
Polyklonal |
|
Wirt
|
|
|
Reaktivität
|
|
|
Applikation
|
Western Blot (WB) (25), Immunfluoreszenz (IF) (20), Durchflusszytometrie (FACS) (18), ELISA (11), Immunhistochemie (Gefrierschnitte) (IHC (fro)) (8), Immunhistochemie (Paraffinschnitte) (IHC (p)) (8), Enzyme Immunoassay (EIA) (7), Immunpräzipitation (IP) (6), Immunhistochemie (IHC) (4), Immunhistochemie (formalinfixierte Schnitte) (IHC (f)) (2), Dot Blot (Dot) (1), Immunzytochemie (ICC) (1), Immunoelectron Microscopy (IEM) (1)
|
| Produktnummer |
ABIN308181 |
| Menge |
100µ (Varianten) |
| Preis |
272,94 € Zzgl. Versandkosten €20,00 und MWSt
|
| Lieferung nach |
|
| Verfügbarkeit |
Lieferung in 5 Werktagen |
|
Immunogen
|
A 14 amino acid synthetic peptide from the human NEDD8 conjugated to Dip. Tox. Produced in: NZ white rabbit.
|
|
Format
|
Antiserum, Lyophilized
|
|
Beschreibung
|
Ubiquitin-like protein which plays an important role in cell cycle control and embryogenesis. Covalent attachment to its substrates requires prior activation by the E1 complex UBE1C-APPBP1 and linkage to the E2 enzyme UBE2M. Attachment of NEDD8 to cullins activates their associated E3 ubiquitin ligase activity, and thus promotes polyubiquitination and proteasomal degradation of cyclins and other regulatory proteins
|
|
Spezifität
|
Confirmed by immunohistochemical analysis of human brain. Specific detection in neurons, glial inclusions and Lewy bodies.
|
|
Applikationshinweise
|
Immunohistochemistry and 1 site ELISA. Immunohistochemistry: Use at 1: 800 dilution. The end user should determine the optimal dilution.
|
|
Reinheit
|
Whole Serum
|
|
Lagerung
|
Long term - 70ºC dry Short term - 20ºC solution or 4ºC with appropriate antibacterial agent. Avoid repeated freezing and thawing. Glycerol (1:1) can be added for additional stability. Reconstitute with addition of 100µl of sterile water.
|
|
Beschränkungen
|
Nur für Forschungszwecke einsetzbar
|
Alternativen zu Antigen "Neural Precursor Cell Expressed, Developmentally Down-Regulated 8 (NEDD8)", Typ "Antikörper" finden
|
Wirte
|
Kaninchen (42), Schaf (3), Maus (2)
|
|
Reaktivitäten
|
Human (39), Ratte (Rattus) (26), Maus (25), Hefe (Saccharomyces Cerevisiae) (2)
|
|
Applikationen
|
Western Blot (WB) (25), Immunfluoreszenz (IF) (20), Durchflusszytometrie (FACS) (18), ELISA (11), Immunhistochemie (Gefrierschnitte) (IHC (fro)) (8), Immunhistochemie (Paraffinschnitte) (IHC (p)) (8), Enzyme Immunoassay (EIA) (7), Immunpräzipitation (IP) (6), Immunhistochemie (IHC) (4), Immunhistochemie (formalinfixierte Schnitte) (IHC (f)) (2), Dot Blot (Dot) (1), Immunzytochemie (ICC) (1), Immunoelectron Microscopy (IEM) (1)
|
|
Konjugate
|
Alexa Flour 488 (1), Alexa Fluor 350 (1), Alexa Fluor 488 (1), Alexa Fluor 555 (1), Alexa Fluor 647 (1), Biotin (1), Cy3 (1), Cy5 (1), Cy5.5 (1), Cy7 (1), FITC (1), Gold (1), HRP (1), PE (1), PE,Cy3 (1), PE,Cy5 (1), PE,Cy5.5 (1), PE,Cy7 (1), RBITC (1)
|
|
Epitope
|
N-Term (7), C-Term (3)
|