5mC Antikörper

Details zu Produkt Nr. ABIN3071645, Anbieter: Anmelden zum Anzeigen
Antigen
Reaktivität
Human, Maus
Wirt
Maus
Klonalität
Monoklonal
Applikation
Chromatin Immunoprecipitation (ChIP)
Optionen
Hersteller
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Hersteller Produkt- Nr.
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Spezifität Recognises the C-terminal peptide of human histone H3.
Reinigung Protein G (affinity purified)
Hintergrund 5mC (5---Methylcytosine) is a region of DNA that has been epigenetically modified through the addition of a methyl group at the 5th carbon position of cytosine. DNA methylation is a repressive histone modification that is associated with switching off gene expression. This methylation generally occurs at CpG islands and is also associated with genomic imprinting. Aberrant DNA methylation is linked to disease including many cancers.
Applikationshinweise Chromatrap technology: 1:4 (gDNA:antibody)
Please note: Optimal antibody dilutions should be determined by the user.
Beschränkungen Nur für Forschungszwecke einsetzbar
Format Liquid
Konzentration 2 mg/mL
Buffer Purified antibody (from supernatant) containing PBS + 0.1 % sodium azide.
Konservierungsmittel Sodium azide
Vorsichtsmaßnahmen This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handhabung Avoid multiple free/thaw cycles as this may denature the antibody
Lagerung -20 °C
Haltbarkeit 12 months
Bilder des Herstellers
Methylated DNA Immunoprecipitation (MeDIP) image for anti-5mC antibody (ABIN3071645) Methylated DNA Immunoprecipitation (MeDIP) assays were performed with 500ng of genomi...
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