FBXW7 Antikörper
Kurzübersicht für FBXW7 Antikörper (ABIN307140)
Target
Alle FBXW7 Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
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Verwendungszweck
- Rabbit anti Human FBXW7
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Kreuzreaktivität
- Human
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Produktmerkmale
- Substrate recognition component of a SCF (SKP1-CUL1-F-box protein) E3 ubiquitin-protein ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins. Probably recognizes and binds to phosphorylated target proteins. Involved in the degradation of cyclin E, NOTCH1 released notch intracellular domain (NICD), and probably PSEN1.
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Aufreinigung
- Ammonium Sulfate Precipitation
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Immunogen
- Synthetic peptide dervied from the human FBXW7 protein
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anti-F-Box and WD Repeat Domain Containing 7 (FBXW7) (C-Term) antibody
FBXW7 Reaktivität: Human, Maus, Ratte, Hund, Rind (Kuh), Kaninchen, Meerschweinchen, Pferd, Zebrafisch (Danio rerio) WB, IHC Wirt: Kaninchen Polyclonal unconjugated
anti-F-Box and WD Repeat Domain Containing 7 (FBXW7) (AA 501-600) antibodyFBXW7 Reaktivität: Human, Maus, Ratte WB, ELISA, IF (p), IHC (p), IF (cc), IHC (fro) Wirt: Kaninchen Polyclonal unconjugated
anti-F-Box and WD Repeat Domain Containing 7 (FBXW7) (AA 599-707) antibodyFBXW7 Reaktivität: Human WB, ELISA, IHC (p) Wirt: Maus Monoclonal 3D1 unconjugated
anti-F-Box and WD Repeat Domain Containing 7 (FBXW7) (AA 1-627) antibodyFBXW7 Reaktivität: Human WB Wirt: Maus Polyclonal unconjugated
anti-F-Box and WD Repeat Domain Containing 7 (FBXW7) (AA 279-515) antibodyFBXW7 Reaktivität: Human WB, IHC, IP, ICC Wirt: Kaninchen Polyclonal unconjugated
anti-F-Box and WD Repeat Domain Containing 7 (FBXW7) (AA 599-707) antibodyFBXW7 Reaktivität: Human WB, ELISA Wirt: Maus Polyclonal unconjugated
anti-F-Box and WD Repeat Domain Containing 7 (FBXW7) (AA 1-707) antibodyFBXW7 Reaktivität: Human IHC, ELISA Wirt: Kaninchen Polyclonal unconjugated
anti-F-Box and WD Repeat Domain Containing 7 (FBXW7) (AA 599-708) antibodyFBXW7 Reaktivität: Human WB, IHC, ELISA, IHC (p) Wirt: Maus Monoclonal 3D1 unconjugated
anti-F-Box and WD Repeat Domain Containing 7 (FBXW7) (C-Term) antibodyFBXW7 Reaktivität: Human, Maus, Ratte, Hund, Rind (Kuh), Schwein, Kaninchen, Meerschweinchen, Pferd, Zebrafisch (Danio rerio), Drosophila melanogaster, Affe, Xenopus laevis, Hamster, Fledermaus, Huhn WB, IHC, IHC (p) Wirt: Kaninchen Polyclonal unconjugated
anti-F-Box and WD Repeat Domain Containing 7 (FBXW7) (AA 251-300) antibodyFBXW7 Reaktivität: Maus, Ratte, Hamster WB, IHC, IHC (p) Wirt: Kaninchen Polyclonal unconjugated
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Applikationshinweise
- Antibody can be used for Western blotting (1-5 μg/mL). Optimal concentration should be evaluated by serial dilutions.
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Buffer
- phosphate buffered saline with 0.08 % sodium azide
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Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Lagerung
- -20 °C
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Informationen zur Lagerung
- Product should be stored at -20°C. Aliquot to avoid freeze/thaw cycles
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- FBXW7 (F-Box and WD Repeat Domain Containing 7 (FBXW7))
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Andere Bezeichnung
- FBXW7
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Hintergrund
- F-box and WD-40 domain protein 7, FBXW7, CDC4
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UniProt
- Q969H0
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Pathways
- Notch Signalweg, EGFR Signaling Pathway
Target
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