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Antikörper
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anti-F-Box and WD Repeat Domain Containing 7 (FBXW7) Antikörper
F-Box and WD Repeat Domain Containing 7 (FBXW7) Antikörper
| Antigen |
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| Synonyme |
AGO, CDC4, FBW6, FBW7, FBX30, FBXW6, SEL10, FBXO30, SEL-10, FLJ16457, DKFZp686F23254, cdc4 |
| Klonalität |
Polyklonal |
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Wirt
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Reaktivität
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Applikation
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| Produktnummer |
ABIN307140 |
| Menge |
100 ug (1 mg/ml) |
| Preis |
276,92 € Zzgl. Versandkosten €20,00 und MWSt
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| Lieferung nach |
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| Verfügbarkeit |
Lieferung in 5 bis 7 Werktagen |
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Weitere Bezeichnung
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FBXW7
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Swiss-Prot
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Q969H0
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Beschreibung
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Substrate recognition component of a SCF (SKP1-CUL1-F-box protein) E3 ubiquitin-protein ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins. Probably recognizes and binds to phosphorylated target proteins. Involved in the degradation of cyclin E, NOTCH1 released notch intracellular domain (NICD), and probably PSEN1. Synonyms: F-box and WD-40 domain protein 7, FBXW7, CDC4.
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Applikationshinweise
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Antibody can be used for Western blotting (1-5 ug/ml). Positive Control: Widely expressed in most human tissues..
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Konzentration
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1 mg/ml
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Lagerung
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Product should be stored at -20C. Aliquot to avoid freeze/thaw cycles
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Beschränkungen
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Nur für Forschungszwecke einsetzbar
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Alternativen zu Antigen "F-Box and WD Repeat Domain Containing 7 (FBXW7)", Typ "Antikörper" finden
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Wirte
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Kaninchen (19), Maus (5)
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Reaktivitäten
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Human (21), Maus (2), Rind (Kuh) (1), Hund (1), Fruchtfliege (Drosophila melanogaster) (1)
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Applikationen
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Western Blot (WB) (19), ELISA (5), Enzyme Immunoassay (EIA) (5), Immunhistochemie (Paraffinschnitte) (IHC (p)) (3), ELISA (Detektionsantikörper) (2), Immunpräzipitation (IP) (2), Immunfluoreszenz (IF) (1)
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Epitope
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isoform 2 (2), isoform 1 (1)
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Alternativen 
