V-Akt Murine Thymoma Viral Oncogene Homolog 1 (AKT1) Antikörper

Antigen: V-Akt Murine Thymoma Viral Oncogene Homolog 1 (AKT1)

Synonyme: AKT, PKB, RAC, PRKBA, MGC99656, PKB-ALPHA, RAC-ALPHA, Akt, pkb, xAct, akt-1, v-akt, v-akt1, AKT1, AKT/PKB, D-Akt, DAKT1, DAKT1/PKB, DPKB, DRAC-PK, DRAC-PK66; DRAC-PK85, Dakt, PKB/AKT, PKB/dAKT, RacPK, dAKT/dPKB, dAkt/PKB, l(3)04226, l(3)89Bq, DmelCG4006, CG4006

Klonalität: Monoklonal (9Q7)

Wirt: Maus

Reaktivität: Human, Maus, Ratte (Rattus)

Applikation: Western Blot (WB)

Produktnummer: ABIN307039

Produktbeschreibung

Weitere Bezeichnung: Akt

Swiss-Prot: P31749

Isotyp: IgG3  (Passende Sekundärantikörper)

Klon: 9Q7

Beschreibung: AKT is a serine/threonine kinase that plays an important role in multiple biological responses including metabolism, cell survival and growth by phosphorylating many proteins including GSK-3 , caspase-9, BAD, and the Forkhead Transcription Factor. AKT is activated by PI3K, which in turn can interact with FAK and other cytoskeletal-associated proteins, thereby linking activation to the cytoskeleton. AKT/PKB is constitutively active in many types of human cancer, and contributes to tumor progression by promoting angiogenesis and cell invasiveness. AKT is fully activated by phosphorylation of threonine 308 by PDK1 and serine 473 by PDK2. The reactivity of this antibody with AKT2 and AKT3 has not been tested. Synonyms: Protein Kinase B, RAC-alpha, EC 2.7.11.1, RAC-PK-alpha, PKB, C-AKT.

Synonyme: AKT, PKB, RAC, PRKBA, MGC99656, PKB-ALPHA, RAC-ALPHA, Akt, pkb, xAct, akt-1, v-akt, v-akt1, AKT1, AKT/PKB, D-Akt, DAKT1, DAKT1/PKB, DPKB, DRAC-PK, DRAC-PK66; DRAC-PK85, Dakt, PKB/AKT, PKB/dAKT, RacPK, dAKT/dPKB, dAkt/PKB, l(3)04226, l(3)89Bq, DmelCG4006, CG4006

Anwendungen

Applikationshinweise: For Western blotting, the recommended concentration is 1 g/mL . Positive Control: Positive Control: Human Jurkat cells, mouse 3T3-L1 cells, and rat PC-12 cells. Found in all human cell types so far analyzed. Found in the cytoplasm (and in the nucleus after activation by integrin-linked protein kinase 1).

Lagerung: Product should be stored at -20C. Aliquot to avoid freeze/thaw cycles

Beschränkungen: Nur für Forschungszwecke einsetzbar