Apoptosis Inhibitor of Macrophages Antikörper

Antigen: Apoptosis Inhibitor of Macrophages

Klonalität: Polyklonal

Wirt: Kaninchen

Reaktivität: Human, Maus

Applikation: Western Blot (WB)

Produktnummer: ABIN306979

Produktbeschreibung

Isotyp: IgG  (Passende Sekundärantikörper)

Beschreibung: Apoptosis inhibitor of macrophages (AIM) is a member of the scavenger receptor cysteine-rich domain superfamily (SRCR-SF) initially identified as an inducible cell surface ligand of CD5. It was shown that AIM functions in the thymus as the inducer of resistance to apoptosis within CD4+/CD8+ thymocytes and as the supporter of the viability of these cells before thymic selection. AIM was also shown to support macrophage survival and enhance their phagocytic function. More recent experiments using recombinant AIM significantly inhibited apoptosis of NKT and T cells obtained from C. parvum-stimulated livers in vitro, suggesting that AIM functions to induce resistance to apoptosis in these cells and supports host defense against inflammation during infection. Synonyms: Apoptosis inhibitor of macrophages, API6, API6, SP alpha, CD5L.

Anwendungen

Applikationshinweise: AIM antibody can be used for the detection of AIM by Western blot at 0.5

Konzentration: 0.5 mg/ml

Lagerung: Product should be stored at -20C. Aliquot to avoid freeze/thaw cycles

Beschränkungen: Nur für Forschungszwecke einsetzbar