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Amyloid beta (A4) Precursor Protein (APP) (C-Term) Antikörper
| Antigen | Amyloid beta (A4) Precursor Protein (APP) |
| Synonyme | APP, APP-like, APPL, Abeta, BcDNA:GH04413, EG:65F1.5, DmelCG7727, CG7727, AAA, AD1, PN2, ABPP, APPI, CVAP, ABETA, CTFgamma, aaa, ad1, pn2, abpp, appi, cvap, abeta, MGC88882, ctfgamma |
| Epitope |
Alternativen C-Term |
| Klonalität | Polyklonal |
| Wirt |
Alternativen Kaninchen |
| Reaktivität |
Alternativen Human, Maus, Ratte (Rattus) |
| Applikation |
Alternativen Western Blot (WB)
|
| Produktnummer | ABIN306764 |
| Menge | 100 ug (0.5 mg/ml) |
| Preis | 272,82 € Zzgl. Versandkosten €20,00 und MWSt |
| Lieferung nach |
|
| Verfügbarkeit | Lieferung in 5 bis 7 Werktagen |
Produktbeschreibung
| Weitere Bezeichnung | Amyloid Precursor Protein (APP) (CT) |
| Swiss-Prot | P05067 |
| Isotyp | IgG (Passende Sekundärantikörper) |
| Beschreibung | Accumulation of the amyloid- peptide (A ) in the cerebral cortex is a critical event in the pathogenesis of Alzheimer's disease. The amyloid protein precursor (APP) is cleaved by secretase, producing a soluble derivative of the protein and a membrane anchored 99-amino acid carboxy-terminal fragment (C99). The C99 fragment serves as substrate for secretase to generate the 4 kDa amyloid- peptide (A ), which is deposited in the brains of all suffers of Alzheimer's disease. Synonyms: Alzheimer disease amyloid protein, ABPP. APPI, PreA4, Cerebral vascular amyloid peptide. |
Anwendungen
| Applikationshinweise | Detects APP and C99 fragment by Western blot at 0.5 to 1 ug/ml. Detects an approximately 120 kDa band in human, mouse and rat brain tissue lysates. Positive Control: Murine brain lysate. |
| Konzentration | 0.5 mg/ml |
| Lagerung | Product should be stored at -20C. Aliquot to avoid freeze/thaw cycles |
| Beschränkungen | Nur für Forschungszwecke einsetzbar |
Alternativen
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