Produktbeschreibung » anti-apoptotic chromatin condensation inducer 1 (ACIN1/ACINUS) Antikörper

Antigen	Apoptotic chromatin condensation inducer 1 (ACIN1/ACINUS)
Swiss-Prot	Q9UKV3
Reaktivität	Human
Wirt	Kaninchen
Klonalität	Polyklonal
Isotyp	IgG »Passende Sekundärantikörper
Beschreibung	Chromatin condensation and nuclear fragmentation (CCNF) is the hallmark of apoptosis. CCNF is triggered by the activation of members of caspase family, caspase activated DNase (CAD/DFF40), and several novel proteins including AIF and CIDE (1). A new inducer of chromatin condensation was recently identified and designated Acinus (for apoptotic chromatin condensation inducer in the nucleus). Acinus is cleaved by caspase-3 and an additional unknown protease generating a small active peptide p17, which causes chromatin condensation in vitro when it is added to purified nuclei. Acinus also induces apoptotic chromatin condensation in cells. Acinus is ubiquitously expressed. Three different spliced forms of Acinus have been identified in human and mouse and designated AcinusL, AcinusS and AcinusS' (2). Synonyms: Apoptotic chromatin condensation inducer in the nucleus, ACINUS, KIAA0670.

Anwendungen » anti-apoptotic chromatin condensation inducer 1 (ACIN1/ACINUS) Antikörper

Applikation	Western Blot (WB) » Hier finden Sie 2 Protokolle zu den gelisteten Anwendungen
Applikationshinweise	Detects Acinus by Western blot at 0.25 to 0.5 ug/ml. Detects a 220 kDa band in K562 cell lysate. Positive Control: K562 cell lysate.
Konzentration	0.5 mg/ml
Lagerung	Product should be stored at -20C. Aliquot to avoid freeze/thaw cycles
Forschungsgebiet	Zellzyklus, Apoptose/Nekrose
Beschränkungen	Nur für Forschungszwecke einsetzbar

Antigen:	Apoptotic chromatin condensation inducer 1 (ACIN1/ACINUS)
Klonalität:	Polyklonal
Applikation:	Western Blot (WB)
Reaktivität:	Human
Wirt:	Kaninchen
Menge:	100 ug (0.5 mg/ml) (Produktvarianten)
Preis:	294,09 € (Zzgl. Versandkosten und MWSt)
Bestellnummer:	ABIN306733
Verfügbarkeit:	Lieferbar innerhalb von 5 bis 10 Werktagen