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Apoptotic Chromatin Condensation Inducer 1 (ACIN1) (C-Term) Antikörper
| Antigen | Apoptotic Chromatin Condensation Inducer 1 (ACIN1) |
| Synonyme |
ACN, ACINUS, fSAP152, KIAA0670, DKFZp667N107, Acn, Acinus, C79325, acinusL, acinusS, mKIAA0670, 2610036I19Rik, 2610510L13Rik, acinus, acinusb, fi14c05, wu:fe06a10, wu:fi14c05, acinusa, acinusl, wu:fb0 ...
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| Epitope |
 Alternativen C-Term |
| Klonalität | Polyklonal |
| Wirt |
Alternativen Kaninchen |
| Reaktivität |
Alternativen Human |
| Applikation |
Alternativen Western Blot (WB)
|
| Produktnummer | ABIN306733 |
| Menge | 100 ug (0.5 mg/ml) (Varianten) |
| Preis | 272,82 € Zzgl. Versandkosten €20,00 und MWSt |
| Lieferung nach |
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| Verfügbarkeit | Lieferung in 5 bis 7 Werktagen |
Produktbeschreibung
| Weitere Bezeichnung | Acinus (CT) |
| Swiss-Prot | Q9UKV3 |
| Isotyp | IgG (Passende Sekundärantikörper) |
| Beschreibung | Chromatin condensation and nuclear fragmentation (CCNF) is the hallmark of apoptosis. CCNF is triggered by the activation of members of caspase family, caspase activated DNase (CAD/DFF40), and several novel proteins including AIF and CIDE (1). A new inducer of chromatin condensation was recently identified and designated Acinus (for apoptotic chromatin condensation inducer in the nucleus). Acinus is cleaved by caspase-3 and an additional unknown protease generating a small active peptide p17, which causes chromatin condensation in vitro when it is added to purified nuclei. Acinus also induces apoptotic chromatin condensation in cells. Acinus is ubiquitously expressed. Three different spliced forms of Acinus have been identified in human and mouse and designated AcinusL, AcinusS and AcinusS' (2). Synonyms: Apoptotic chromatin condensation inducer in the nucleus, ACINUS, KIAA0670. |
| Synonyme | ACN, ACINUS, fSAP152, KIAA0670, DKFZp667N107, Acn, Acinus, C79325, acinusL, acinusS, mKIAA0670, 2610036I19Rik, 2610510L13Rik, acinus, acinusb, fi14c05, wu:fe06a10, wu:fi14c05, acinusa, acinusl, wu:fb04g06, wu:fb40f03, wu:fb68h03, wu:fb80f07, wu:fc12e10, ik:tdsubc_2g5, si:zc14a17.12, xx:tdsubc_2g5, acn, MGC69430, MGC132201 |
Anwendungen
| Applikationshinweise | Detects Acinus by Western blot at 0.25 to 0.5 ug/ml. Detects a 220 kDa band in K562 cell lysate. Positive Control: K562 cell lysate. |
| Konzentration | 0.5 mg/ml |
| Lagerung | Product should be stored at -20C. Aliquot to avoid freeze/thaw cycles |
| Forschungsgebiet | Zellzyklus, Apoptose/Nekrose |
| Beschränkungen | Nur für Forschungszwecke einsetzbar |
Alternativen
Alternativen zu Antigen "Apoptotic Chromatin Condensation Inducer 1 (ACIN1)", Typ "Antikörper" finden
| Wirte | Kaninchen (68), Maus (1) |
| Reaktivitäten | Human (65), Maus (24), Ratte (Rattus) (21), Rind (Kuh) (16), Hund (16), Pferd (16), Huhn (1), Schwein (1) |
| Applikationen | Western Blot (WB) (51), Immunfluoreszenz (IF) (24), Durchflusszytometrie (FACS) (18), Enzyme Immunoassay (EIA) (7), ELISA (4), Immunhistochemie (Paraffinschnitte) (IHC (p)) (3), Immunpräzipitation (IP) (3), Immunhistochemie (formalinfixierte Schnitte) (IHC (f)) (2), Immunoelectron Microscopy (IEM) (1) |
| Konjugate | Alexa Flour 488 (1), Alexa Fluor 350 (1), Alexa Fluor 488 (1), Alexa Fluor 555 (1), Alexa Fluor 647 (1), Biotin (1), Cy3 (1), Cy5 (1), Cy5.5 (1), Cy7 (1), FITC (1), Gold (1), HRP (1), PE (1), PE,Cy3 (1), PE,Cy5 (1), PE,Cy5.5 (1), PE,Cy7 (1), RBITC (1) |
| Epitope | C-Term (4), N-Term (1), internal (1) |
