14-3-3 protein (C-Term) Antikörper

Antigen: 14-3-3 protein (C-Term)

Klonalität: Polyklonal

Wirt: Kaninchen

Reaktivität: Ratte (Rattus)

Applikation: Western Blot (WB)

Produktnummer: ABIN304779

Produktbeschreibung

Immunogen: Peptide corresponding to amino acid residues from the C-terminal region of the 14-3-3 protein, conjugated to keyhole limpet hemocyanin (KLH).

Beschreibung: Gene: 14-3-3

Spezifität: Recognizes rat 14-3-3 protein, a highly conserved, ubiquitously expressed protein family.14-3-3 proteins form homo- and heterodimers that can interact with a variety of cellular proteins that are typically phosphorylated on serine or threonine residues.14-3-3 proteins regulate cellular processes such as trafficking, cell-cycle regulatory pathways and signal transduction. Brain tissue contains the highest concentration of 14-3-3 proteins and the proteins have been found in the cerebral spinal fluid of patients with certain neurodegenerative disease such as Creutzfeldt-Jakob disease and scrapie.14-3-3 proteins might also contribute to Alzheimer's and Parkinson's diseases, Miller-Dieker syndrome and spinocerebellar ataxia type 1.14-3-3 has also been implicated in cancer Predicted Reactivities: Cow (Bovine),Chicken,Dog (Canine),Xenopus laevis,Human,Mouse (Murine).

Anwendungen

Applikationshinweise: WB (1:1000)

Reinigung: Affinity Chromatography

Buffer: 10 mM HEPES, pH 7.5, 150 mM sodium chloride, 0.09% sodium azide, 50% glycerol, 0.01% BSA.

Lagerung: Long term: -20°C, Short term: -20°C

Beschränkungen: Nur für Forschungszwecke einsetzbar