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AIMP2 Antikörper (Middle Region)

AIMP2 Reaktivität: Human, Ratte WB, IHC (p) Wirt: Kaninchen Polyclonal unconjugated
Produktnummer ABIN3044411
  • Target Alle AIMP2 Antikörper anzeigen
    AIMP2 (Aminoacyl tRNA Synthetase Complex-Interacting Multifunctional Protein 2 (AIMP2))
    Bindungsspezifität
    • 15
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 298-320, Middle Region
    Reaktivität
    • 25
    • 22
    • 21
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    Human, Ratte
    Wirt
    • 36
    • 4
    Kaninchen
    Klonalität
    • 38
    • 2
    Polyklonal
    Konjugat
    • 19
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser AIMP2 Antikörper ist unkonjugiert
    Applikation
    • 33
    • 13
    • 13
    • 8
    • 7
    • 5
    • 4
    • 3
    • 1
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
    Verwendungszweck
    Rabbit IgG polyclonal antibody for Aminoacyl tRNA synthase complex-interacting multifunctional protein 2(AIMP2) detection. Tested with WB, IHC-P in Human,Mouse,Rat.
    Sequenz
    NVQRWMRSCE NLAPFNTALK LLK
    Kreuzreaktivität (Details)
    Predicted Cross Reactivity: mouse
    No cross reactivity with other proteins.
    Predicted Cross Reactivity: Species predicted to be fit for the product based on sequence similarities.
    Produktmerkmale
    Rabbit IgG polyclonal antibody for Aminoacyl tRNA synthase complex-interacting multifunctional protein 2(AIMP2) detection. Tested with WB, IHC-P in Human,Mouse,Rat.
    Gene Name: aminoacyl tRNA synthetase complex-interacting multifunctional protein 2
    Protein Name: Aminoacyl tRNA synthase complex-interacting multifunctional protein 2
    Aufreinigung
    Immunogen affinity purified.
    Immunogen
    A synthetic peptide corresponding to a sequence in the middle region of human AIMP2/p38(298-320aa NVQRWMRSCENLAPFNTALKLLK), different from the related rat and mouse sequences by three amino acids.
    Isotyp
    IgG
    Top Product
    Discover our top product AIMP2 Primärantikörper
  • Applikationshinweise
    WB: Concentration: 0.1-0.5 μg/mL, Tested Species: Human, Rat, Predicted Species: Mouse
    IHC-P: Concentration: 0.5-1 μg/mL, Tested Species: Human, Rat, Predicted Species: Mouse, Epitope Retrieval by Heat: Boiling the paraffin sections in 10 mM citrate buffer, pH 6.0, for 20 mins is required for the staining of formalin/paraffin sections.
    Notes: Tested Species: Species with positive results. Predicted Species: Species predicted to be fit for the product based on sequence similarities. Other applications have not been tested. Optimal dilutions should be determined by end users.
    Kommentare

    Antibody can be supported by chemiluminescence kit ABIN921124 in WB, supported by ABIN921231 in IHC(P).

    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Lyophilized
    Rekonstitution
    Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
    Konzentration
    500 μg/mL
    Buffer
    Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Thimerosal, 0.05 mg Sodium azide.
    Konservierungsmittel
    Thimerosal (Merthiolate), Sodium azide
    Vorsichtsmaßnahmen
    This product contains Sodium azide and Thimerosal (Merthiolate): POISONOUS AND HAZARDOUS SUBSTANCES which should be handled by trained staff only.
    Handhabung
    Avoid repeated freezing and thawing.
    Lagerung
    4 °C/-20 °C
    Informationen zur Lagerung
    At -20°C for one year. After reconstitution, at 4°C for one month.
    It can also be aliquotted and stored frozen at -20 °C for a longer time. Avoid repeated freezing and thawing.
    Haltbarkeit
    12 months
  • Sun, Yang, Wang, Sun, Dong: "Crocin attenuates cisplatin-induced liver injury in the mice." in: Human & experimental toxicology, Vol. 33, Issue 8, pp. 855-62, (2015) (PubMed).

    Zheng, Liu, Liu, Ma, Zhou, Chen, Chang, Wang, Yang, He: "Cucurbitacin B inhibits growth and induces apoptosis through the JAK2/STAT3 and MAPK pathways in SH?SY5Y human neuroblastoma cells." in: Molecular medicine reports, Vol. 10, Issue 1, pp. 89-94, (2014) (PubMed).

    Zhao, Li: "Altholactone induces reactive oxygen species-mediated apoptosis in bladder cancer T24 cells through mitochondrial dysfunction, MAPK-p38 activation and Akt suppression." in: Oncology reports, Vol. 31, Issue 6, pp. 2769-75, (2014) (PubMed).

  • Target
    AIMP2 (Aminoacyl tRNA Synthetase Complex-Interacting Multifunctional Protein 2 (AIMP2))
    Andere Bezeichnung
    AIMP2 (AIMP2 Produkte)
    Synonyme
    jtv1 antikoerper, MGC53242 antikoerper, pro0992 antikoerper, JTV1 antikoerper, JTV-1 antikoerper, P38 antikoerper, AA407136 antikoerper, AA407225 antikoerper, Aimp2(p38) antikoerper, Jtv1 antikoerper, aminoacyl tRNA synthetase complex-interacting multifunctional protein 2 L homeolog antikoerper, aminoacyl tRNA synthetase complex-interacting multifunctional protein 2 antikoerper, aminoacyl tRNA synthetase complex interacting multifunctional protein 2 antikoerper, aimp2.L antikoerper, aimp2 antikoerper, AIMP2 antikoerper, Aimp2 antikoerper
    Hintergrund
    AIMP2, Aminoacyl tRNA synthetase complex-interacting multifunctional protein 2, also known as AIMP2, is an enzyme that in humans is encoded by the AIMP2 gene. AIMP2 encodes a predicted 312-amino acid protein. The AIMP2 gene is located on chromosome 7p22 flanked by two genes, HRI and PMS2. AIMP2 and HRI overlap slightly and are arranged in a tail-to-tail fashion. AIMP2 and PMS2 are separated by approximately 200 base pairs and are arranged head-to-head. AIMP2 is transcribed in the opposite direction compared to HRI and PMS2. AIMP2 is a scaffold required for the assembly and stability of the multi-tRNA synthetase complex. AIMP2 can work as a mediator of TGF-beta signaling and its functional importance in the control of MYC during lung differentiation.

    Synonyms: Aimp2 antibody|AIMP2_HUMAN antibody|Aminoacyl tRNA synthase complex-interacting multifunctional protein 2 antibody|Aminoacyl tRNA synthetase complex interacting multifunctional protein 2 antibody|ARS interacting multi functional protein 2 antibody|JTV 1 antibody|JTV 1 protein antibody|JTV1 antibody|Multisynthase complex auxiliary component p38 antibody|Multisynthetase complex auxiliary component p38 antibody|P38 antibody|PRO0992 antibody|Protein JTV 1 antibody|Protein JTV-1 antibody|tRNA SYNTHETASE COFACTOR p38 antibody
    UniProt
    Q13155
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