FGFR1 Antikörper (C-Term)

Produktnummer ABIN3044410

Produktdetails anti-FGFR1 Antikörper

Target: FGFR1 (Fibroblast Growth Factor Receptor 1 (FGFR1))

Bindungsspezifität: AA 806-822, C-Term

Reaktivität: Human, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser FGFR1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Verwendungszweck: Rabbit IgG polyclonal antibody for Fibroblast growth factor receptor 1(FGFR1) detection. Tested with WB, IHC-P in Human,Mouse,Rat.

Sequenz: CLPRHPAQLA NCGLKRR

Kreuzreaktivität (Details): Predicted Cross Reactivity: mouse
No cross reactivity with other proteins.
Predicted Cross Reactivity: Species predicted to be fit for the product based on sequence similarities.

Produktmerkmale: Rabbit IgG polyclonal antibody for Fibroblast growth factor receptor 1(FGFR1) detection. Tested with WB, IHC-P in Human,Mouse,Rat.
Gene Name: fibroblast growth factor receptor 1
Protein Name: Fibroblast growth factor receptor 1(FGFR-1/bFGF-R-1)

Aufreinigung: Immunogen affinity purified.

Immunogen: A synthetic peptide corresponding to a sequence at the C-terminus of human FGFR1(806-822aa CLPRHPAQLANCGLKRR), different from the related mouse sequence by two amino acids and rat sequence by three amino acids.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB: Concentration: 0.1-0.5 μg/mL, Tested Species: Human, Rat, Predicted Species: Mouse
IHC-P: Concentration: 0.5-1 μg/mL, Tested Species: Human, Rat, Predicted Species: Mouse, Epitope Retrieval by Heat: Boiling the paraffin sections in 10 mM citrate buffer, pH 6.0, for 20 mins is required for the staining of formalin/paraffin sections.
Notes: Tested Species: Species with positive results. Predicted Species: Species predicted to be fit for the product based on sequence similarities. Other applications have not been tested. Optimal dilutions should be determined by end users.

Kommentare:

Antibody can be supported by chemiluminescence kit ABIN921124 in WB, supported by ABIN921231 in IHC(P).

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Rekonstitution: Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Konzentration: 500 μg/mL

Buffer: Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Thimerosal, 0.05 mg Sodium azide.

Konservierungsmittel: Thimerosal (Merthiolate), Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide and Thimerosal (Merthiolate): POISONOUS AND HAZARDOUS SUBSTANCES which should be handled by trained staff only.

Handhabung: Avoid repeated freezing and thawing.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: At -20°C for one year. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20 °C for a longer time. Avoid repeated freezing and thawing.

Haltbarkeit: 12 months

Referenzen für anti-FGFR1 Antikörper (ABIN3044410)

Lin, Jia, Zeng, Mi, Zhang: "Basic FGF promotes proliferation of ovarian granulosa cells in the laying chickens via FGFR1 and PKC pathway." in: Reproduction in domestic animals = Zuchthygiene, Vol. 47, Issue 1, pp. 135-42, (2012) (PubMed).

Zhang, Zhang, Zhuang, Lu: "Cytotoxicity of a novel fibroblast growth factor receptor targeted immunotoxin on a human ovarian teratocarcinoma cell line." in: Cancer biotherapy & radiopharmaceuticals, Vol. 21, Issue 4, pp. 321-32, (2006) (PubMed).

Details zu FGFR1

Target: FGFR1 (Fibroblast Growth Factor Receptor 1 (FGFR1))

Andere Bezeichnung: FGFR1 (FGFR1 Produkte)

Synonyme: FGFR antikoerper, fgfr antikoerper, X1FGFR antikoerper, XFGFR-1 antikoerper, XFGFRA2 antikoerper, bfgfr antikoerper, cek antikoerper, fgfr1 antikoerper, flg antikoerper, flt-2 antikoerper, flt2 antikoerper, kal2 antikoerper, ogd antikoerper, xfgfr1 antikoerper, CG7223 antikoerper, CT22273 antikoerper, CT39172 antikoerper, DFGF-R1 antikoerper, DFGF-R2 antikoerper, DFR-1 antikoerper, DFR1 antikoerper, DFR1/DFGF-R2 antikoerper, DPR3 antikoerper, DTRK(FR1) antikoerper, Dfr-1 antikoerper, Dfr1 antikoerper, DmHD-38 antikoerper, Dmel\\CG7223 antikoerper, Dtk1 antikoerper, EMS2 antikoerper, FGF-R2 antikoerper, FGFR2 antikoerper, FR1 antikoerper, Fr1 antikoerper, HD-38 antikoerper, HTL/FGFR1 antikoerper, Htl antikoerper, Tk1 antikoerper, dtk1 antikoerper, i100 antikoerper, i150 antikoerper, i79 antikoerper, j372 antikoerper, cd331 antikoerper, fgfbr antikoerper, fgfr-1 antikoerper, hbgfr antikoerper, n-sam antikoerper, ach antikoerper, cd333 antikoerper, cek2 antikoerper, fgfr-3 antikoerper, hsfgfr3ex antikoerper, jtk4 antikoerper, BFGFR antikoerper, CD331 antikoerper, CEK antikoerper, FGFBR antikoerper, FGFR-1 antikoerper, FLG antikoerper, FLT-2 antikoerper, FLT2 antikoerper, HBGFR antikoerper, HH2 antikoerper, KAL2 antikoerper, N-SAM antikoerper, OGD antikoerper, bFGF-R-1 antikoerper, AW208770 antikoerper, Eask antikoerper, Fgfr-1 antikoerper, Flt-2 antikoerper, Hspy antikoerper, FLG-1 antikoerper, FGFRI antikoerper, x1fgfr antikoerper, cb231 antikoerper, sb:cb231 antikoerper, fibroblast growth factor receptor antikoerper, fibroblast growth factor receptor 1 S homeolog antikoerper, basic fibroblast growth factor receptor 1 antikoerper, heartless antikoerper, fibroblast growth factor receptor 1 antikoerper, fibroblast growth factor receptor 3 (achondroplasia, thanatophoric dwarfism) L homeolog antikoerper, Fibroblast growth factor receptor 1 antikoerper, fibroblast growth factor receptor 1 L homeolog antikoerper, fibroblast growth factor receptor 1a antikoerper, FGFR antikoerper, fgfr antikoerper, fgfr1.S antikoerper, CpipJ_CPIJ005849 antikoerper, htl antikoerper, fgfr1 antikoerper, fgfr3.L antikoerper, FGFR1 antikoerper, Fgfr1 antikoerper, fgfr1.L antikoerper, fgfr1a antikoerper

Hintergrund: FGFR1, Fibroblast growth factor receptor 1, also known as basic fibroblast growth factor receptor 1, fms-related tyrosine kinase-2/Pfeiffer syndrome, and CD331, is a receptor tyrosine kinase whose ligands are specific members of the fibroblast growth factor family. The FGFR1 gene is localized to 8p12-p11.2 by in situ hybridization. FGFR1 is essential for the normal formation of the organ of Corti and that phenotype severity observed in FGFR1 mutants is dependent on the dose of FGFR1.Mutations in this gene have been associated with Pfeiffer syndrome, Jackson-Weiss syndrome, Antley-Bixler syndrome, osteoglophonic dysplasia, squamous cell lung cancer and autosomal dominant Kallmann syndrome 2.

Synonyms: Basic fibroblast growth factor receptor 1 antibody|bFGF R antibody|bFGF-R-1 antibody|BFGFR antibody|C FGR antibody|CD 331 antibody|CD331 antibody|CD331 antigen antibody|CEK antibody|FGFBR antibody|FGFR 1 antibody|FGFR-1 antibody|FGFR1 antibody|FGFR1_HUMAN antibody|Fibroblast growth factor receptor 1 antibody|FLG antibody|FLG protein antibody|FLJ14326 antibody|FLT 2 antibody|FLT-2 antibody|FLT2 antibody|FMS like tyrosine kinase 2 antibody|Fms like tyrosine kinase 2 antibody|Fms related tyrosine kinase 2 antibody|Fms related tyrosine kinase 2 Pfeiffer syndrome antibody|Fms-like tyrosine kinase 2 antibody|H2 antibody|H3 antibody|H4 antibody|H5 antibody|HBGFR antibody|Heparin binding growth factor receptor antibody|Hydroxyaryl protein kinase antibody|KAL 2 antibody|KAL2 antibody|MFR antibody|N SAM antibody|N sam tyrosine kinase antibody|Protein tyrosine kinase antibody|Proto-oncogene c-Fgr antibody|Tyrosylprotein kinase antibody

UniProt: P11362

Pathways: RTK Signalweg, Fc-epsilon Rezeptor Signalübertragung, EGFR Signaling Pathway, Neurotrophin Signalübertragung, Sensory Perception of Sound, Stem Cell Maintenance, S100 Proteine