Myoglobin Antikörper (C-Term)

Produktnummer ABIN3044306

Produktdetails anti-Myoglobin Antikörper

Target: Myoglobin (MB)

Bindungsspezifität: AA 138-154, C-Term

Reaktivität: Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser Myoglobin Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Verwendungszweck: Rabbit IgG polyclonal antibody for Myoglobin(MB) detection. Tested with WB, IHC-P in Mouse,Rat.

Sequenz: LFRNDIAAKY KELGFQG

Kreuzreaktivität (Details): Predicted Cross Reactivity: mouse
No cross reactivity with other proteins.
Predicted Cross Reactivity: Species predicted to be fit for the product based on sequence similarities.

Produktmerkmale: Rabbit IgG polyclonal antibody for Myoglobin(MB) detection. Tested with WB, IHC-P in Mouse,Rat.
Gene Name: myoglobin
Protein Name: myoglobin

Aufreinigung: Immunogen affinity purified.

Immunogen: A synthetic peptide corresponding to a sequence at the C-terminus of mouse Myoglobin(138-154aa LFRNDIAAKYKELGFQG), identical to the related rat sequence.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB: Concentration: 0.1-0.5 μg/mL, Tested Species: Rat, Predicted Species: Mouse
IHC-P: Concentration: 0.5-1 μg/mL, Tested Species: Rat, Predicted Species: Mouse, Epitope Retrieval by Heat: Boiling the paraffin sections in 10 mM citrate buffer, pH 6.0, for 20 mins is required for the staining of formalin/paraffin sections.
Notes: Tested Species: Species with positive results. Predicted Species: Species predicted to be fit for the product based on sequence similarities. Other applications have not been tested. Optimal dilutions should be determined by end users.

Kommentare:

Antibody can be supported by chemiluminescence kit ABIN921124 in WB, supported by ABIN921231 in IHC(P).

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Rekonstitution: Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Konzentration: 500 μg/mL

Buffer: Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Thimerosal, 0.05 mg Sodium azide.

Konservierungsmittel: Thimerosal (Merthiolate), Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide and Thimerosal (Merthiolate): POISONOUS AND HAZARDOUS SUBSTANCES which should be handled by trained staff only.

Handhabung: Avoid repeated freezing and thawing.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: At -20°C for one year. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20 °C for a longer time. Avoid repeated freezing and thawing.

Haltbarkeit: 12 months

Referenzen für anti-Myoglobin Antikörper (ABIN3044306)

Xu, He, Zhang, Fan, Zhao, Xu, Nie, Li, Huang, Lu, Xu: "Synthesis and in vitro evaluation of a hyaluronic acid-quantum dots-melphalan conjugate." in: Carbohydrate polymers, Vol. 121, pp. 132-9, (2015) (PubMed).

Peng, Yanjiao, Ai-guo, Pengtao, Jianhua, Ju, Hongsheng, Xichen: "A fine balance between CCNL1 and TIMP1 contributes to the development of breast cancer cells." in: Biochemical and biophysical research communications, Vol. 409, Issue 2, pp. 344-9, (2011) (PubMed).

Details zu Myoglobin

Target: Myoglobin (MB)

Andere Bezeichnung: Myoglobin (MB Produkte)

Synonyme: PVALB antikoerper, AI325109 antikoerper, zgc:65819 antikoerper, zgc:77764 antikoerper, MB antikoerper, DKFZp468H096 antikoerper, myg antikoerper, mb antikoerper, MYF4 antikoerper, bHLHc3 antikoerper, myo antikoerper, Myoglobin antikoerper, myoglobin antikoerper, myogenin antikoerper, MB antikoerper, Mb antikoerper, mb antikoerper, myg antikoerper, Myog antikoerper

Hintergrund: Myoglobin(MB) also known as PVALB, is a single-chain globular protein of 153 or 154 amino acids, containing a heme (iron-containing porphyrin) prosthetic group in the center around which the remaining apoprotein folds. It is a member of the globin superfamily and is expressed in skeletal and cardiac muscles. This gene is mapped to chromosome 22q11-q13. Myoglobin is released from damaged muscle tissue (rhabdomyolysis), which has very high concentrations of myoglobin. The released myoglobin is filtered by the kidneys but is toxic to the renal tubular epithelium and so may cause acute renal failure.

Synonyms: MB antibody|MGC13548 antibody|MYG_HUMAN antibody|Myoglobin antibody|PVALB antibody

UniProt: P04247

Pathways: Brown Fat Cell Differentiation