Adaptor Protein, phosphotyrosine Interaction, PH Domain and Leucine Zipper Containing 1 (APPL1) (AA 138-158), (N-Term) Antikörper

Details zu Produkt Nr. ABIN3044289, Anbieter: Anmelden zum Anzeigen
Antigen
  • APPL
  • DIP13alpha
  • 2900057D21Rik
  • 7330406P05Rik
  • AI585782
  • AW209077
  • BB022931
  • C88264
  • DIP13
  • RGD1309388
  • adaptor protein, phosphotyrosine interaction, PH domain and leucine zipper containing 1
  • APPL1
  • Appl1
Epitop
AA 138-158, N-Term
14
9
5
4
4
3
3
3
2
1
1
1
1
1
1
1
1
1
Reaktivität
Human, Ratte (Rattus)
67
33
21
7
5
3
3
3
3
3
1
1
Wirt
Kaninchen
46
20
3
Klonalität
Polyklonal
Konjugat
Unkonjugiert
1
1
1
1
1
1
Applikation
Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)
63
35
18
11
3
3
1
1
1
Optionen
Hersteller
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Verwendungszweck Rabbit IgG polyclonal antibody for DCC-interacting protein 13-alpha(APPL1) detection. Tested with WB, IHC-P in Human,Mouse,Rat.
Immunogen A synthetic peptide corresponding to a sequence at the N-terminus of human APPL(138-158aa NDHDAAINRYSRLSKKRENDK), identical to the related mouse and rat sequences.
Sequenz NDHDAAINRY SRLSKKREND K
Isotyp IgG
Kreuzreaktivität (Details) Predicted Cross Reactivity: mouse
No cross reactivity with other proteins.
Predicted Cross Reactivity: Species predicted to be fit for the product based on sequence similarities.
Produktmerkmale Rabbit IgG polyclonal antibody for DCC-interacting protein 13-alpha(APPL1) detection. Tested with WB, IHC-P in Human,Mouse,Rat.
Gene Name: adaptor protein, phosphotyrosine interaction, PH domain and leucine zipper containing 1
Protein Name: DCC-interacting protein 13-alpha(Dip13-alpha)
Reinigung Immunogen affinity purified.
Andere Bezeichnung APPL1 (APPL1 Antibody Abstract)
Hintergrund DCC-interacting protein 13-alpha(APPL1) is a protein that in humans is encoded by the APPL1 gene. The APPL1 gene is mapped to 3q21.1-p13.3. It is said to contain 709 amino acids and share 54 % amino acid identity with APPL2. APPL is highly expressed in skeletal muscle, heart, ovary, and pancreas, tissues in which AKT2 mRNA is abundant. It has been regarded as an adaptor that may tether inactive AKT2 to the PI3K in the cytoplasm and thereby may expedite recruitment of AKT2 and PI3K to the cell membrane upon mitogenic stimulation.

Synonyms: Adapter protein containing PH domain antibody|Adaptor Protein Containing pH Domain antibody|Adaptor protein containing pH domain PTB domain and leucine zipper motif 1 antibody|Adaptor protein containing pH domain PTB domain and leucine zipper motif antibody|AKT2 INTERACTOR antibody|APPL 1 antibody|APPL1 antibody|DCC interacting protein 13 alpha antibody|DCC-interacting protein 13-alpha antibody|DIP 13 alpha antibody|DIP13 alpha antibody|Dip13-alpha antibody|DIP13alpha antibody|DP13A_HUMAN antibody|KIAA1428 antibody|PTB domain and leucine zipper motif 1 antibody|PTB Domain and Leucine Zipper Motif antibody|Signaling adaptor protein DIP13alpha antibody
Applikationshinweise WB: Concentration: 0.1-0.5 μg/mL, Tested Species: Human, Rat, Predicted Species: Mouse
IHC-P: Concentration: 0.5-1 μg/mL, Tested Species: Rat, Predicted Species: Human, Mouse, Epitope Retrieval by Heat: Boiling the paraffin sections in 10 mM citrate buffer, pH 6.0, for 20 mins is required for the staining of formalin/paraffin sections.
Notes: Tested Species: Species with positive results. Predicted Species: Species predicted to be fit for the product based on sequence similarities. Other applications have not been tested. Optimal dilutions should be determined by end users.
Kommentare

Antibody can be supported by chemiluminescence kit ABIN921124 in WB, supported by ABIN921231 in IHC(P).

Beschränkungen Nur für Forschungszwecke einsetzbar
Format Lyophilized
Rekonstitution Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
Konzentration 500 μg/mL
Buffer Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Thimerosal, 0.05 mg Sodium azide.
Konservierungsmittel Thimerosal (Merthiolate), Sodium azide
Vorsichtsmaßnahmen This product contains Sodium azide and Thimerosal (Merthiolate): POISONOUS AND HAZARDOUS SUBSTANCES which should be handled by trained staff only.
Handhabung Avoid repeated freezing and thawing.
Lagerung 4 °C/-20 °C
Informationen zur Lagerung At -20°C for one year. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20 °C for a longer time. Avoid repeated freezing and thawing.
Haltbarkeit 12 months
Bilder des Herstellers
Western Blotting (WB) image for anti-Adaptor Protein, phosphotyrosine Interaction, PH Domain and Leucine Zipper Containing 1 (APPL1) (AA 138-158), (N-Term) antibody (ABIN3044289) Anti-APPL antibody, Western blotting WB: HELA Cell Lysate
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