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MFGE8 Antikörper (Middle Region)

MFGE8 Reaktivität: Human WB, IHC (p) Wirt: Kaninchen Polyclonal unconjugated
Produktnummer ABIN3044017
  • Target Alle MFGE8 Antikörper anzeigen
    MFGE8 (Milk Fat Globule-EGF Factor 8 Protein (MFGE8))
    Bindungsspezifität
    • 15
    • 9
    • 7
    • 6
    • 5
    • 4
    • 3
    • 2
    • 1
    • 1
    • 1
    AA 165-180, Middle Region
    Reaktivität
    • 62
    • 10
    • 4
    • 3
    Human
    Wirt
    • 44
    • 22
    • 4
    • 1
    Kaninchen
    Klonalität
    • 48
    • 23
    Polyklonal
    Konjugat
    • 44
    • 5
    • 4
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser MFGE8 Antikörper ist unkonjugiert
    Applikation
    • 60
    • 24
    • 21
    • 20
    • 13
    • 13
    • 11
    • 11
    • 11
    • 7
    • 4
    • 3
    • 3
    • 2
    • 2
    • 2
    Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
    Verwendungszweck
    Rabbit IgG polyclonal antibody for Lactadherin(MFGE8) detection. Tested with WB, IHC-P in Human.
    Sequenz
    NGHEFDFIHD VNKKHK
    Kreuzreaktivität (Details)
    No cross reactivity with other proteins.
    Produktmerkmale
    Rabbit IgG polyclonal antibody for Lactadherin(MFGE8) detection. Tested with WB, IHC-P in Human.
    Gene Name: milk fat globule-EGF factor 8 protein
    Protein Name: Lactadherin
    Aufreinigung
    Immunogen affinity purified.
    Immunogen
    A synthetic peptide corresponding to a sequence in the middle region of human Human Milk Fat Globule 1(165-180aa NGHEFDFIHDVNKKHK).
    Isotyp
    IgG
    Top Product
    Discover our top product MFGE8 Primärantikörper
  • Applikationshinweise
    WB: Concentration: 0.1-0.5 μg/mL, Tested Species: Human, The detection limit for MFGE8 is approximately 0.5 ng/lane under reducing conditions.
    IHC-P: Concentration: 0.5-1 μg/mL, Tested Species: Human, Epitope Retrieval by Heat: Boiling the paraffin sections in 10 mM citrate buffer, pH 6.0, for 20 mins is required for the staining of formalin/paraffin sections.
    Notes: Tested Species: Species with positive results. Predicted Species: Species predicted to be fit for the product based on sequence similarities. Other applications have not been tested. Optimal dilutions should be determined by end users.
    Kommentare

    Antibody can be supported by chemiluminescence kit ABIN921124 in WB, supported by ABIN921231 in IHC(P).

    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Lyophilized
    Rekonstitution
    Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
    Konzentration
    500 μg/mL
    Buffer
    Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Thimerosal, 0.05 mg Sodium azide.
    Konservierungsmittel
    Thimerosal (Merthiolate), Sodium azide
    Vorsichtsmaßnahmen
    This product contains Sodium azide and Thimerosal (Merthiolate): POISONOUS AND HAZARDOUS SUBSTANCES which should be handled by trained staff only.
    Handhabung
    Avoid repeated freezing and thawing.
    Lagerung
    4 °C/-20 °C
    Informationen zur Lagerung
    At -20°C for one year. After reconstitution, at 4°C for one month.
    It can also be aliquotted and stored frozen at -20 °C for a longer time. Avoid repeated freezing and thawing.
    Haltbarkeit
    12 months
  • Becker-Dreps, Choi, Stamper, Vilchez, Velasquez, Moon, Hudgens, Jiang, Permar: "Innate Immune Factors in Mothers' Breast Milk and Their Lack of Association With Rotavirus Vaccine Immunogenicity in Nicaraguan Infants." in: Journal of the Pediatric Infectious Diseases Society, Vol. 6, Issue 1, pp. 87-90, (2018) (PubMed).

  • Target
    MFGE8 (Milk Fat Globule-EGF Factor 8 Protein (MFGE8))
    Andere Bezeichnung
    MFGE8 (MFGE8 Produkte)
    Synonyme
    BA46 antikoerper, EDIL1 antikoerper, HMFG antikoerper, HsT19888 antikoerper, MFG-E8 antikoerper, MFGM antikoerper, OAcGD3S antikoerper, SED1 antikoerper, SPAG10 antikoerper, hP47 antikoerper, ba46 antikoerper, edil1 antikoerper, oacgd3s antikoerper, MGC75581 antikoerper, hst19888 antikoerper, MGC145109 antikoerper, MFGE8 antikoerper, mfge8 antikoerper, zgc:154157 antikoerper, MGC99228 antikoerper, AA408458 antikoerper, AI325141 antikoerper, Mfgm antikoerper, P47 antikoerper, lactadherin antikoerper, AGS antikoerper, MFGME8 antikoerper, MFGMP-E8 antikoerper, im:6895406 antikoerper, mfge8l antikoerper, zgc:110846 antikoerper, milk fat globule-EGF factor 8 protein antikoerper, milk fat globule-EGF factor 8 protein b antikoerper, milk fat globule-EGF factor 8 protein L homeolog antikoerper, milk fat globule-EGF factor 8 protein a antikoerper, MFGE8 antikoerper, mfge8 antikoerper, mfge8b antikoerper, mfge8.L antikoerper, Mfge8 antikoerper, mfge8a antikoerper
    Hintergrund
    MFGE8(Milk Fat Globule-Egf Factor 8), also called as Lactadherin or SED1, is a protein which in humans is encoded by the MFGE8 gene. Mfge8 is secreted protein found in vertebrates, including mammals as well as birds. By fluorescence in situ hybridization, Collins et al.(1997) mapped the MFGE8 gene to chromosome 15q25. Hanayama et al.(2002) found that MFGE8 is a factor that links apoptotic cells to phagocytes. MFGE8 specifically bound to apoptotic cells by recognizing aminophospholipids such as phosphatidylserine. MFGE8, when engaged by phospholipids, bound to cells via its RGD motif. It bound particularly strongly to cells expressing alpha-V-beta-3 integrin. Bu et al.(2007) showed that Mfge8 was expressed in intestinal lamina propria macrophages in mice. Using a wound-healing assay, they showed that Mfge8 promoted migration of intestinal epithelial cells through a PKC-epsilon(PRKCE)-dependent mechanism.

    Synonyms: BA 46 antibody|BA46 antibody|Breast epithelial antigen BA46 antibody|Contains Medin antibody|EDIL 1 antibody|EDIL1 antibody|HMFG antibody|hP47 antibody|HsT19888 antibody|Lactadherin antibody|Lactadherin precursor antibody|Medin antibody|MFG E8 antibody|MFG-E8 antibody|MFGE 8 antibody|MFGE8 antibody|MFGE8 protein antibody|MFGM antibody|MFGM_HUMAN antibody|Milk fat globule EGF factor 8 antibody|Milk fat globule EGF factor 8 protein antibody|Milk fat globule-EGF factor 8 antibody|O acetyl disialoganglioside synthase antibody|OAcGD3S antibody|SED1 antibody|SPAG10 antibody|Sperm associated antigen 10 antibody|Sperm surface protein hP47 antibody
    UniProt
    Q08431
    Pathways
    SARS-CoV-2 Protein Interaktom
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