SMAD5 Antikörper (SMAD, Mothers Against DPP Homolog 5) (AA 248-267)

Details for Product anti-SMAD5 Antibody No. ABIN3043980, Anbieter: Anmelden zum Anzeigen
Antigen
  • SBN
  • fb67b04
  • mad
  • madh5
  • sb:cb400
  • smd5
  • wu:fb67b04
  • XSmad4alpha
  • dpc4
  • jip
  • jv5-1
  • madh4
  • smad10
  • smad5
  • xsmad4
  • DWFC
  • JV5-1
  • MADH5
  • 1110051M15Rik
  • AI451355
  • Dwf-C
  • Madh5
  • MusMLP
  • SMAD5
  • DKFZp468M0619
  • SMAD family member 5
  • MAD homolog 5 (Drosophila)
  • SMAD family member 4, gene 2
  • SMAD5
  • smad5
  • smad4.2-b
  • Smad5
Epitop
AA 248-267, Middle Region
20
16
11
10
5
4
3
3
2
2
1
1
1
1
1
1
1
1
1
Reaktivität
Human, Ratte (Rattus)
105
46
38
8
7
6
6
5
5
4
3
2
2
1
Wirt
Kaninchen
67
39
1
Klonalität
Polyklonal
Konjugat
Dieser SMAD5 Antikörper ist unkonjugiert
3
3
3
3
3
3
Applikation
Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)
102
57
28
25
19
18
9
3
2
1
1
1
1
Optionen
Hersteller
Anmelden zum Anzeigen
Hersteller Produkt- Nr.
Anmelden zum Anzeigen
Request

Dieses Produkt umsonst

Schicken Sie uns Ihren Validierungsvorschlag. Ich möchte dieses Produkt validieren

Mehr erfahren

Bilder

Verwendungszweck Rabbit IgG polyclonal antibody for Mothers against decapentaplegic homolog 5(SMAD5) detection. Tested with WB, IHC-P in Human,Mouse,Rat.
Immunogen A synthetic peptide corresponding to a sequence in the middle region of human SMAD5(248-267aa IPQIMPSISSRDVQPVAYEE), identical to the related rat sequence, and different from the related mouse sequence by one amino acid.
Sequenz IPQIMPSISS RDVQPVAYEE
Isotyp IgG
Kreuzreaktivität (Details) Predicted Cross Reactivity: mouse
No cross reactivity with other proteins.
Predicted Cross Reactivity: Species predicted to be fit for the product based on sequence similarities.
Produktmerkmale Rabbit IgG polyclonal antibody for Mothers against decapentaplegic homolog 5(SMAD5) detection. Tested with WB, IHC-P in Human,Mouse,Rat.
Gene Name: SMAD family member 5
Protein Name: Mothers against decapentaplegic homolog 5
Reinigung Immunogen affinity purified.
Andere Bezeichnung SMAD5 (SMAD5 Antibody Abstract)
Hintergrund Mother against decapentaplegic homolog 5 also known as SMAD5 is a protein that in humans is encoded by the SAMD5 gene. It belongs to the SMAD family of proteins, which belong to the TGFbeta superfamily of modulators. The gene was assigned to human chromosome 5q31. Like many other TGFbeta family members SMAD5 is involved in cell signalling and modulates signals of bone morphogenetic proteins(BMP's). It may play a role in the pathway where TGFbeta is an inhibitor of hematopoietic progenitor cells.

Synonyms: DKFZp781C1895 antibody|DKFZp781O1323 antibody|Dwfc antibody|hSmad 5 antibody|hSmad5 antibody|JV5 1 antibody|JV5-1 antibody|MAD homolog 5 antibody|MAD mothers against decapentaplegic homolog 5 antibody|MAD, mothers against decapentaplegic homolog 5 antibody|MADH 5 antibody|MADH5 antibody|Mothers against decapentaplegic homolog 5 antibody|Mothers against DPP homolog 5 antibody|MusMLP antibody|SMA and MAD related protein 5 antibody|SMAD 5 antibody|SMAD family member 5 antibody|SMAD mothers against DPP homolog 5 antibody|Smad5 antibody|SMAD5_HUMAN antibody
UniProt Q99717
Forschungsgebiet Organogenesis, Signaling, Transcription Factors
Applikationshinweise WB: Concentration: 0.1-0.5 μg/mL, Tested Species: Human, Rat, Predicted Species: Mouse, The detection limit for SMAD5 is approximately 1.5 ng/lane under reducing conditions.
IHC-P: Concentration: 0.5-1 μg/mL, Tested Species: Human, Rat, Predicted Species: Mouse, Epitope Retrieval by Heat: Boiling the paraffin sections in 10 mM citrate buffer, pH 6.0, for 20 mins is required for the staining of formalin/paraffin sections.
Notes: Tested Species: Species with positive results. Predicted Species: Species predicted to be fit for the product based on sequence similarities. Other applications have not been tested. Optimal dilutions should be determined by end users.
Kommentare

Antibody can be supported by chemiluminescence kit ABIN921124 in WB, supported by ABIN921231 in IHC(P).

Beschränkungen Nur für Forschungszwecke einsetzbar
Format Lyophilized
Rekonstitution Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
Konzentration 500 μg/mL
Buffer Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Thimerosal, 0.05 mg Sodium azide.
Konservierungsmittel Thimerosal (Merthiolate), Sodium azide
Vorsichtsmaßnahmen This product contains Sodium azide and Thimerosal (Merthiolate): POISONOUS AND HAZARDOUS SUBSTANCES which should be handled by trained staff only.
Handhabung Avoid repeated freezing and thawing.
Lagerung 4 °C/-20 °C
Informationen zur Lagerung At -20°C for one year. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20 °C for a longer time. Avoid repeated freezing and thawing.
Haltbarkeit 12 months
Bilder des Herstellers
Immunohistochemistry (IHC) image for anti-SMAD5 Antikörper (SMAD, Mothers Against DPP Homolog 5) (AA 248-267) (ABIN3043980) Anti-SMAD5 antibody, IHC(P) IHC(P): Human Intestinal Cancer Tissue
Immunohistochemistry (IHC) image for anti-SMAD5 Antikörper (SMAD, Mothers Against DPP Homolog 5) (AA 248-267) (ABIN3043980) Anti-SMAD5 antibody, IHC(P) IHC(P): Rat Intestine Tissue
Western Blotting (WB) image for anti-SMAD5 Antikörper (SMAD, Mothers Against DPP Homolog 5) (AA 248-267) (ABIN3043980) anti-SMAD, Mothers Against DPP Homolog 5 (SMAD5) (AA 248-267), (Middle Region) antibody (Image 3)
Immunohistochemistry (IHC) image for anti-SMAD5 Antikörper (SMAD, Mothers Against DPP Homolog 5) (AA 248-267) (ABIN3043980) Anti-SMAD5 antibody, IHC(P) IHC(P): Human Lung Cancer Tissue