SLC2A2 Antikörper (C-Term)

Produktnummer ABIN3043928

Produktdetails anti-SLC2A2 Antikörper

Target: SLC2A2 (Solute Carrier Family 2 (Facilitated Glucose Transporter), Member 2 (SLC2A2))

Bindungsspezifität: AA 486-514, C-Term

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser SLC2A2 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Verwendungszweck: Rabbit IgG polyclonal antibody for Solute carrier family 2, facilitated glucose transporter member 2(SLC2A2) detection. Tested with WB, IHC-P in Human.

Sequenz: ETKGKSFEEI AAEFQKKSGS AHRPKAAVE

Kreuzreaktivität (Details): No cross reactivity with other proteins.

Produktmerkmale: Rabbit IgG polyclonal antibody for Solute carrier family 2, facilitated glucose transporter member 2(SLC2A2) detection. Tested with WB, IHC-P in Human.
Gene Name: solute carrier family 2 (facilitated glucose transporter), member 2
Protein Name: Solute carrier family 2, facilitated glucose transporter member 2

Aufreinigung: Immunogen affinity purified.

Immunogen: A synthetic peptide corresponding to a sequence at the C-terminus of human SLC2A2 (486-514aa ETKGKSFEEIAAEFQKKSGSAHRPKAAVE), different from the related mouse sequence by five amino acids, and from the related rat sequence by seven amino acids.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB: Concentration: 0.1-0.5 μg/mL, Tested Species: Human, The detection limit for SLC2A2 is approximately 0.1 ng/lane under reducing conditions.
IHC-P: Concentration: 0.5-1 μg/mL, Tested Species: Human, Epitope Retrieval by Heat: Boiling the paraffin sections in 10 mM citrate buffer, pH 6.0, for 20 mins is required for the staining of formalin/paraffin sections.
Notes: Tested Species: Species with positive results. Other applications have not been tested. Optimal dilutions should be determined by end users.

Kommentare:

Antibody can be supported by chemiluminescence kit ABIN921124 in WB, supported by ABIN921231 in IHC(P).

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Rekonstitution: Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Konzentration: 500 μg/mL

Buffer: Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freezing and thawing.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: At -20°C for one year. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20 °C for a longer time. Avoid repeated freezing and thawing.

Referenzen für anti-SLC2A2 Antikörper (ABIN3043928)

Wu, Guo, Lu, Wu, Pan, Su: "Impact of perinatal exposure to acetaminophen on hepatocellular metabolic function in offspring." in: American journal of translational research, Vol. 8, Issue 12, pp. 5646-5652, (2017) (PubMed).

Details zu SLC2A2

Target: SLC2A2 (Solute Carrier Family 2 (Facilitated Glucose Transporter), Member 2 (SLC2A2))

Andere Bezeichnung: SLC2A2 (SLC2A2 Produkte)

Synonyme: glut2 antikoerper, wu:fb62h10 antikoerper, slc2a2 antikoerper, MGC83262 antikoerper, SLC2A2 antikoerper, GLUT2 antikoerper, GTT2 antikoerper, Glut2 antikoerper, AI266973 antikoerper, Glut-2 antikoerper, solute carrier family 2 (facilitated glucose transporter), member 2 antikoerper, solute carrier family 2 member 2 L homeolog antikoerper, solute carrier family 2 member 2 antikoerper, solute carrier family 2, facilitated glucose transporter member 2 antikoerper, slc2a2 antikoerper, slc2a2.L antikoerper, SLC2A2 antikoerper, LOC100534484 antikoerper, Slc2a2 antikoerper

Hintergrund: SLC2A2, also known as Glucose transporter 2 (GLUT2), is a transmembrane carrier protein that enables protein facilitatedglucose movement across cell membranes. This gene encodes an integral plasma membrane glycoprotein of the liver, islet beta cells, intestine, and kidney epithelium. The encoded protein mediates facilitated bidirectional glucose transport. Because of its low affinity for glucose, it has been suggested as a glucose sensor. Mutations in this gene are associated with susceptibility to diseases, including Fanconi-Bickel syndrome and noninsulin-dependent diabetes mellitus (NIDDM). Alternative splicing results in multiple transcript variants of this gene.

Synonyms: liver antibody|Glucose Transporter 2 antibody|Glucose Transporter GLUT2 antibody|Glucose transporter type 2 antibody|Glucose transporter type 2 liver antibody|Glucose transporter, liver/islet antibody|GLUT-2 antibody|GLUT2 antibody|GTR2_HUMAN antibody|GTT2 antibody| SLC2A2 antibody|Solute carrier family 2 (facilitated glucose transporter) member 2 antibody|Solute carrier family 2 facilitated glucose transporter member 2 antibody|Solute carrier family 2, facilitated glucose transporter member 2 antibody

Gen-ID: 6514

UniProt: P11168

Pathways: Warburg Effekt