Calretinin Antikörper (C-Term)

Produktnummer ABIN3043772

Produktdetails anti-Calretinin Antikörper

Target: Calretinin (CALB2) (Calbindin 2 (CALB2))

Bindungsspezifität: AA 234-262, C-Term

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser Calretinin Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Verwendungszweck: Rabbit IgG polyclonal antibody for Calretinin(CALB2) detection. Tested with WB, IHC-P in Human,Mouse,Rat.

Sequenz: EMNIQQLTNY RKSVMSLAEA GKLYRKDLE

Kreuzreaktivität (Details): No cross reactivity with other proteins.

Produktmerkmale: Rabbit IgG polyclonal antibody for Calretinin(CALB2) detection. Tested with WB, IHC-P in Human,Mouse,Rat.
Gene Name: calbindin 2
Protein Name: Calretinin

Aufreinigung: Immunogen affinity purified.

Immunogen: A synthetic peptide corresponding to a sequence at the C-terminal of human Calretinin(234-262aa EMNIQQLTNYRKSVMSLAEAGKLYRKDLE), different from the related mouse and rat sequences by one amino acid.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB: Concentration: 0.1-0.5 μg/mL, Tested Species: Mouse, Rat, Predicted Species: Human
IHC-P: Concentration: 0.5-1 μg/mL, Tested Species: Human, Mouse, Rat, Epitope Retrieval by Heat: Boiling the paraffin sections in 10 mM citrate buffer, pH 6.0, for 20 mins is required for the staining of formalin/paraffin sections.
Notes: Tested Species: Species with positive results. Predicted Species: Species predicted to be fit for the product based on sequence similarities. Other applications have not been tested. Optimal dilutions should be determined by end users.

Kommentare:

Antibody can be supported by chemiluminescence kit ABIN921124 in WB, supported by ABIN921231 in IHC(P).

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Rekonstitution: Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Konzentration: 500 μg/mL

Buffer: Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freezing and thawing.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: At -20°C for one year. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20 °C for a longer time. Avoid repeated freezing and thawing.

Details zu Calretinin

Target: Calretinin (CALB2) (Calbindin 2 (CALB2))

Andere Bezeichnung: CALB2 (CALB2 Produkte)

Synonyme: CAB29 antikoerper, CAL2 antikoerper, CR antikoerper, calb2l antikoerper, wu:fq18e08 antikoerper, zgc:73115 antikoerper, calb2 antikoerper, wu:fq17g09 antikoerper, zgc:73099 antikoerper, calbindin 2 antikoerper, calbindin 2a antikoerper, calbindin 2b antikoerper, CALB2 antikoerper, Calb2 antikoerper, calb2a antikoerper, calb2b antikoerper

Hintergrund: Calretinin, also known as 29 kDa calbindin, is a vitamin D-dependent calcium-binding protein involved in calcium signaling. In humans, the calretinin protein is encoded by the CALB2 gene. This gene encodes an intracellular calcium-binding protein belonging to the troponin C superfamily. Members of this protein family have six EF-hand domains which bind calcium. Calretinin is mapped to 16q22.2. This protein plays a role in diverse cellular functions, including message targeting and intracellular calcium buffering. It also functions as a modulator of neuronal excitability and is a diagnostic marker for some human diseases, including Hirschsprung disease and some cancers.

Synonyms: 29 kDa calbindin antibody|CAB 29 antibody|CAB29 antibody|CAL 2 antibody|CAL2 antibody|CALB 2 antibody|CALB2 antibody|CALB2_HUMAN antibody|Calbindin 2 29 kDa antibody|Calbindin 2 antibody|Calbindin D29K antibody|Calbindin2 antibody|Calretinin antibody|CR antibody

Gen-ID: 794

UniProt: P22676