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CCL5 Antikörper (AA 26-91)

CCL5 Reaktivität: Human WB, ELISA Wirt: Kaninchen Polyclonal unconjugated
Produktnummer ABIN3043478
  • Target Alle CCL5 Antikörper anzeigen
    CCL5 (Chemokine (C-C Motif) Ligand 5 (CCL5))
    Bindungsspezifität
    • 38
    • 15
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 26-91
    Reaktivität
    • 78
    • 43
    • 20
    • 19
    • 15
    • 15
    • 9
    • 5
    • 4
    • 3
    • 1
    • 1
    • 1
    Human
    Wirt
    • 105
    • 29
    • 2
    • 1
    • 1
    Kaninchen
    Klonalität
    • 99
    • 38
    Polyklonal
    Konjugat
    • 67
    • 30
    • 14
    • 4
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser CCL5 Antikörper ist unkonjugiert
    Applikation
    • 95
    • 54
    • 51
    • 18
    • 16
    • 14
    • 14
    • 14
    • 14
    • 12
    • 8
    • 8
    • 8
    • 7
    • 5
    • 5
    • 1
    Western Blotting (WB), ELISA
    Verwendungszweck
    Rabbit IgG polyclonal antibody for C-C motif chemokine 5(CCL5) detection. Tested with WB, ELISA in Human.
    Kreuzreaktivität (Details)
    No cross reactivity with other proteins.
    Produktmerkmale
    Rabbit IgG polyclonal antibody for C-C motif chemokine 5(CCL5) detection. Tested with WB, ELISA in Human.
    Gene Name: chemokine (C-C motif) ligand 5
    Protein Name: C-C motif chemokine 5
    Aufreinigung
    Immunogen affinity purified.
    Immunogen
    E. coli-derived human RANTES recombinant protein (Position: Y26-S91). Human RANTES shares 83.3% amino acid (aa) sequence identity with both mouse and rat RANTES.
    Isotyp
    IgG
    Top Product
    Discover our top product CCL5 Primärantikörper
  • Applikationshinweise
    WB: Concentration: 0.1-0.5 μg/mL, Tested Species: Human
    ELISA: Concentration: 0.1-0.5 μg/mL, Tested Species: Human

    Notes: Tested Species: Species with positive results.
    Other applications have not been tested. Optimal dilutions should be determined by end users.
    Kommentare

    Antibody can be supported by chemiluminescence kit ABIN921124 in WB.

    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Lyophilized
    Rekonstitution
    Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
    Konzentration
    500 μg/mL
    Buffer
    Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Sodium azide.
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Handhabung
    Avoid repeated freezing and thawing.
    Lagerung
    4 °C/-20 °C
    Informationen zur Lagerung
    At -20°C for one year. After reconstitution, at 4°C for one month.
    It can also be aliquotted and stored frozen at -20 °C for a longer time. Avoid repeated freezing and thawing.
  • Wei, Feng, Sun, Cheng, Ma, Zhao, Dong, Zhang, Li: "Different locations of RANTES and its receptors on mouse epididymal spermatozoa." in: Reproduction, fertility, and development, (2015) (PubMed).

    Li, Sun, Liao, Ma, Ma, Zhang: "Regulated upon activation normal T-cell expressed and secreted originating from the epididymis differentially associates with viable and defective spermatozoa." in: Fertility and sterility, Vol. 93, Issue 8, pp. 2661-7, (2010) (PubMed).

  • Target
    CCL5 (Chemokine (C-C Motif) Ligand 5 (CCL5))
    Andere Bezeichnung
    CCL5 (CCL5 Produkte)
    Synonyme
    Rantes antikoerper, Scya5 antikoerper, D17S136E antikoerper, RANTES antikoerper, SCYA5 antikoerper, SIS-delta antikoerper, SISd antikoerper, TCP228 antikoerper, eoCP antikoerper, MuRantes antikoerper, C-C motif chemokine 5-like antikoerper, C-C motif chemokine ligand 5 antikoerper, chemokine (C-C motif) ligand 5 antikoerper, LOC100230935 antikoerper, CCL5 antikoerper, Ccl5 antikoerper
    Hintergrund
    Chemokine (C-C motif) ligand 5 (also CCL5) is a protein which in humans is encoded by the CCL5 gene. It is also known as RANTES. This gene is one of several chemokine genes clustered on the q-arm of chromosome 17. Chemokines form a superfamily of secreted proteins involved in immunoregulatory and inflammatory processes. The superfamily is divided into four subfamilies based on the arrangement of the N-terminal cysteine residues of the mature peptide. This chemokine, a member of the CC subfamily, functions as a chemoattractant for blood monocytes, memory T helper cells and eosinophils. It causes the release of histamine from basophils and activates eosinophils. This cytokine is one of the major HIV-suppressive factors produced by CD8+ cells. It functions as one of the natural ligands for the chemokine receptor chemokine (C-C motif) receptor 5 (CCR5), and it suppresses in vitro replication of the R5 strains of HIV-1, which use CCR5 as a coreceptor. Alternative splicing results in multiple transcript variants that encode different isoforms.

    Synonyms: Beta chemokine RANTES precursor antibody|CCL 5 antibody|CCL5 antibody|CCL5_HUMAN antibody|Chemokine (C C motif) ligand 5 antibody| Chemokine CC Motif Ligand 5 antibody|D17S136E antibody|EoCP antibody|Eosinophil chemotactic cytokine antibody|MGC17164 antibody| RANTES(4-68) antibody|Regulated upon activation normally T expressed and presumably secreted antibody|SCYA 5 antibody|SCYA5 antibody| SIS delta antibody|SIS-delta antibody|SISd antibody|Small inducible cytokine A5 (RANTES) antibody|Small inducible cytokine A5 antibody|Small inducible cytokine subfamily A (Cys Cys) member 5 antibody|Small-inducible cytokine A5 antibody|T cell specific protein p288 antibody|T cell specific RANTES protein antibody|T cell-specific protein P228 antibody|T-cell-specific protein RANTES antibody| TCP 228 antibody|TCP228 antibody
    Gen-ID
    6352
    UniProt
    P13501
    Pathways
    Cellular Response to Molecule of Bacterial Origin, Regulation of G-Protein Coupled Receptor Protein Signaling, Smooth Muscle Cell Migration
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