SERPINA1 Antikörper (AA 211-411)

Produktnummer ABIN3043431

Produktdetails anti-SERPINA1 Antikörper

Target: SERPINA1 (serpin Peptidase Inhibitor, Clade A (Alpha-1 Antiproteinase, Antitrypsin), Member 1 (SERPINA1))

Bindungsspezifität: AA 211-411

Reaktivität: Ratte, Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser SERPINA1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Verwendungszweck: Rabbit IgG polyclonal antibody for Alpha-1-antiproteinase(SERPINA1) detection. Tested with WB, IHC-P in Mouse,Rat.

Kreuzreaktivität (Details): No cross reactivity with other proteins.

Produktmerkmale: Rabbit IgG polyclonal antibody for Alpha-1-antiproteinase(SERPINA1) detection. Tested with WB, IHC-P in Mouse,Rat.
Gene Name: serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1
Protein Name: Alpha-1-antiproteinase

Aufreinigung: Immunogen affinity purified.

Immunogen: E.coli-derived rat SERPINA1 recombinant protein (Position: K211-R411). Rat SERPINA1 shares 66% amino acid (aa) sequence identity with human SERPINA1.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB: Concentration: 0.1-0.5 μg/mL, Tested Species: Mouse, Rat, The detection limit for SERPINA1 is approximately 0.1 ng/lane under reducing conditions.
IHC-P: Concentration: 0.5-1 μg/mL, Tested Species: Mouse, Rat, Epitope Retrieval by Heat: Boiling the paraffin sections in 10 mM citrate buffer, pH 6.0, for 20 mins is required for the staining of formalin/paraffin sections.
Notes: Tested Species: Species with positive results. Other applications have not been tested. Optimal dilutions should be determined by end users.

Kommentare:

Antibody can be supported by chemiluminescence kit ABIN921124 in WB, supported by ABIN921231 in IHC(P).

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Rekonstitution: Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Konzentration: 500 μg/mL

Buffer: Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freezing and thawing.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: At -20°C for one year. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20 °C for a longer time. Avoid repeated freezing and thawing.

Referenzen für anti-SERPINA1 Antikörper (ABIN3043431)

Lv, Gao, Liu, Zhang, Huang, Zhu, Zong, Li, Li: "Clinical and pathological characteristics of IgG4-related interstitial lung disease." in: Experimental and therapeutic medicine, Vol. 15, Issue 2, pp. 1465-1473, (2018) (PubMed).

Details zu SERPINA1

Target: SERPINA1 (serpin Peptidase Inhibitor, Clade A (Alpha-1 Antiproteinase, Antitrypsin), Member 1 (SERPINA1))

Andere Bezeichnung: SERPINA1 (SERPINA1 Produkte)

Synonyme: AACT antikoerper, ACT antikoerper, GIG25 antikoerper, A1AT antikoerper, PI antikoerper, alpha-1-PI antikoerper, A1A antikoerper, AAT antikoerper, PI1 antikoerper, PRO2275 antikoerper, alpha1AT antikoerper, Pi antikoerper, Spi1 antikoerper, MGC64429 antikoerper, serpina1d antikoerper, Aps antikoerper, SERPINA3-5 antikoerper, serpin family A member 3 antikoerper, alpha-1-antiproteinase F precursor antikoerper, serpin family A member 1 antikoerper, alpha-1-antitrypsin antikoerper, calumenin antikoerper, serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1 S homeolog antikoerper, serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1 antikoerper, serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 5 antikoerper, SH2B adaptor protein 2 antikoerper, serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 3 antikoerper, serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1 L homeolog antikoerper, SERPINA3 antikoerper, LOC100008973 antikoerper, SERPINA1 antikoerper, LOC100328621 antikoerper, CALU antikoerper, Serpina1 antikoerper, serpina1.S antikoerper, serpina1 antikoerper, SPIA5 antikoerper, Sh2b2 antikoerper, Calu antikoerper, serpina1.L antikoerper

Hintergrund: SERPINA1 is also known as PI, A1A or AAT. The protein encoded by this gene is secreted and is a serine protease inhibitor whose targets include elastase, plasmin, thrombin, trypsin, chymotrypsin, and plasminogen activator. Defects in this gene can cause emphysema or liver disease. Several transcript variants encoding the same protein have been found for this gene.

Synonyms: A1A antibody|A1AT antibody|A1AT_HUMAN antibody|AAT antibody|Alpha 1 antiproteinase antibody|Alpha 1 antitrypsin antibody|Alpha 1 antitrypsin null antibody|Alpha 1 protease inhibitor antibody|Alpha-1 protease inhibitor antibody|Alpha-1-antiproteinase antibody|alpha-1-AT antibody|alpha1 PI antibody|alpha1 proteinase inhibitor antibody|Alpha1AT antibody|Clade A (alpha 1 antiproteinase antitrypsin) member 1 antibody|Dom1 antibody|MGC23330 antibody|MGC9222 antibody|PI antibody|PI1 antibody|PRO2275 antibody|Protease inhibitor 1 (anti elastase) antibody|Serine (or cysteine) proteinase inhibitor clade A member 1 antibody|Serine protease inhibitor 1-1 antibody|Serine protease inhibitor A1a antibody|Serpin A1 antibody|Serpin A1a antibody|Serpin peptidase inhibitor clade A (alpha 1 antiproteinase antitrypsin) member 1 antibody|Serpin peptidase inhibitor clade A member 1 antibody|SerpinA1 antibody|Short peptide from AAT antibody|SPAAT antibody|Spi1-1 antibody

Gen-ID: 24648

UniProt: P17475