HIF3A Antikörper (C-Term)

Produktnummer ABIN3042875

Produktdetails anti-HIF3A Antikörper

Target: HIF3A (Hypoxia Inducible Factor 3, alpha Subunit (HIF3A))

Bindungsspezifität: AA 497-514, C-Term

Reaktivität: Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser HIF3A Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Verwendungszweck: Rabbit IgG polyclonal antibody for Hypoxia-inducible factor 3-alpha(HIF3A) detection. Tested with WB in Human,Rat.

Sequenz: DDDFQLNASE QLPRAYHR

Kreuzreaktivität (Details): Predicted Cross Reactivity: human
No cross reactivity with other proteins.
Predicted Cross Reactivity: Species predicted to be fit for the product based on sequence similarities.

Produktmerkmale: Rabbit IgG polyclonal antibody for Hypoxia-inducible factor 3-alpha(HIF3A) detection. Tested with WB in Human,Rat.
Gene Name: hypoxia inducible factor 3, alpha subunit
Protein Name: Hypoxia-inducible factor 3-alpha

Aufreinigung: Immunogen affinity purified.

Immunogen: A synthetic peptide corresponding to a sequence at the C-terminus of human HIF3(497-514aa DDDFQLNASEQLPRAYHR), different from the related rat and mouse sequences by five amino acids.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB: Concentration: 0.1-0.5 μg/mL, Tested Species: Rat, Predicted Species: Human
Notes: Tested Species: Species with positive results. Predicted Species: Species predicted to be fit for the product based on sequence similarities.
Other applications have not been tested. Optimal dilutions should be determined by end users.

Kommentare:

Antibody can be supported by chemiluminescence kit ABIN921124 in WB.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Rekonstitution: Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Konzentration: 500 μg/mL

Buffer: Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Thimerosal, 0.05 mg Sodium azide.

Konservierungsmittel: Thimerosal (Merthiolate), Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide and Thimerosal (Merthiolate): POISONOUS AND HAZARDOUS SUBSTANCES which should be handled by trained staff only.

Handhabung: Avoid repeated freezing and thawing.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: At -20°C for one year. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20 °C for a longer time. Avoid repeated freezing and thawing.

Haltbarkeit: 12 months

Details zu HIF3A

Target: HIF3A (Hypoxia Inducible Factor 3, alpha Subunit (HIF3A))

Andere Bezeichnung: HIF3A (HIF3A Produkte)

Synonyme: HIF-3A antikoerper, IPAS antikoerper, MOP7 antikoerper, PASD7 antikoerper, bHLHe17 antikoerper, Ipas antikoerper, NEPAS antikoerper, Mop7 antikoerper, HIF3A antikoerper, hypoxia inducible factor 3 alpha subunit antikoerper, hypoxia inducible factor 3, alpha subunit antikoerper, HIF3A antikoerper, Hif3a antikoerper

Hintergrund: Hypoxia-inducible factor 3 alpha, also called MOP7, is a protein that in humans is encoded by the HIF3A gene. HIF3A is mapped to 19q13.32. This gene involved in adaptive response to hypoxia. HIF3A suppresses hypoxia-inducible expression of HIF1A and EPAS1. It binds to core DNA sequence 5'-TACGTG-3' within the hypoxia response element(HRE) of target gene promoters. The complex HIF3A-ARNT activates the transcription of reporter genes driven by HRE. This gene functions as an inhibitor of angiogenesis in the cornea.

Synonyms: Basic-helix-loop-helix-PAS protein MOP7 antibody|bHLHe17 antibody|Class E basic helix-loop-helix protein 17 antibody|HIF 3A antibody|HIF 3A4 antibody|HIF-3-alpha antibody|HIF3 alpha antibody|HIF3-alpha antibody|HIF3-alpha-1 antibody|HIF3A antibody|HIF3A_HUMAN antibody|Hypoxia Inducible Factor 3 alpha antibody|Hypoxia inducible factor 3 alpha subunit antibody|Hypoxia inducible factor three alpha antibody|Hypoxia-inducible factor 3-alpha antibody|Inhibitory PAS domain protein antibody|IPAS antibody|Member of PAS protein 7 antibody|MOP7 antibody|PAS domain-containing protein 7 antibody|PASD7 antibody

UniProt: Q9Y2N7

Pathways: Warburg Effekt